Synthesis of novel Schiff bases using green chemistry techniques; antimicrobial, antioxidant, antiurease activity screening and molecular docking studies

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dc.authoridUSLU, HARUN/0000-0001-8827-8557
dc.authoridMermer, Arif/0000-0002-4789-7180
dc.authoridSirin, Yakup/0000-0002-8759-0132
dc.authoridDemirbas, Ahmet/0000-0002-7474-6783
dc.authoridDemirbas, Neslihan/0000-0002-8444-2011
dc.authorwosidUSLU, HARUN/P-3681-2019
dc.authorwosidDemirbaş, neslihan/AAK-7327-2021
dc.authorwosidSirin, Yakup/AAM-9689-2020
dc.authorwosidMermer, Arif/ABC-8564-2021
dc.authorwosidMermer, Arif/ABE-2124-2021
dc.authorwosidDemirbaş, Ahmet/AAK-6620-2021
dc.contributor.authorMermer, Arif
dc.contributor.authorDemirbas, Neslihan
dc.contributor.authorUslu, Harun
dc.contributor.authorDemirbas, Ahmet
dc.contributor.authorCeylan, Sule
dc.contributor.authorSirin, Yakup
dc.date.accessioned2024-08-04T20:45:41Z
dc.date.available2024-08-04T20:45:41Z
dc.date.issued2019
dc.departmentİnönü Üniversitesien_US
dc.description.abstractSchiff base derivatives were synthesized in this study via conventional, microwave irradiation and ultrasound sonication methods. Optimization conditions were examined for several parameter such as solvent, reaction time and yield. After determining the optimization conditions, the compounds were synthesized by using ultrasound sonication. The structures of the synthesized compounds were examined by spectral data, and the antiurease, antioxidant and antimicrobial activities of the Schiff bases derivatives were investigated due to the imine group (-C=N-) and promising results were obtained. The enzyme inhibitory potentials of these compounds were further validated through molecular docking studies. Also, In Silico ADME prediction studies were calculated for compounds. (C) 2019 Elsevier B.V. All rights reserved.en_US
dc.identifier.doi10.1016/j.molstruc.2018.12.114
dc.identifier.endpage422en_US
dc.identifier.issn0022-2860
dc.identifier.issn1872-8014
dc.identifier.scopus2-s2.0-85060011507en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage412en_US
dc.identifier.urihttps://doi.org/10.1016/j.molstruc.2018.12.114
dc.identifier.urihttps://hdl.handle.net/11616/98609
dc.identifier.volume1181en_US
dc.identifier.wosWOS:000458612300045en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherElsevier Science Bven_US
dc.relation.ispartofJournal of Molecular Structureen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectUltrasound sonicationen_US
dc.subjectMicrowave irradiationen_US
dc.subjectBiological activityen_US
dc.subjectADME predictionen_US
dc.titleSynthesis of novel Schiff bases using green chemistry techniques; antimicrobial, antioxidant, antiurease activity screening and molecular docking studiesen_US
dc.typeArticleen_US

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