The effect of transcatheter aortic valve implantation on ventricular repolarization indices and neutrophil-to-lymphocyte ratio
Yükleniyor...
Dosyalar
Tarih
2020
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Aim: The electrocardiographic QT dispersion (QTd), Tpe/QT ratio and Tpeak-Tend (Tpe) interval have been known as ventricular repolarization indices. Neutrophil–to- lymphocyte ratio (NLR) is an inflammatory marker that is newly described. Increased QTd, Tpe/QT ratio, inflammation and Tpe interval are associated with ventricular arrhythmia (VA). In patients with severe aortic stenosis (AS), VA has a key role in terms of morbidity and mortality. The present study aimed at examining whether transcatheter aortic valve implantation (TAVI) affects ventricular repolarization indices and NLR. Material and Methods: Study population consisted of a total of 44 patients undergoing TAVI. Echocardiographic and laboratory parameters of patients were evaluated before TAVI and sixth month after TAVI. Comparioson of electrocardiographic QTd, Tpe/QT ratio, Tpe interval and NLR of the same petients were made before TAVI and sixth month after TAVI.Results: QT interval, corrected QT interval and heart rate were similar before and after TAVI (p>0.05 for all). There was a statistically significant decrease in QTd (26.0±9.1 vs. 21.3±7.2 ms; p=0.008), Tpe interval (88.43±12.6vs. 78.8±10.1 ms; p0.001), NLR (3.08±2.0 vs. 2.16±0.73; p=0.001) and Tpe/QT ratio ( 0.23±0.3 vs. 0.21±0.1; p=0.024) after TAVI. Morever, the reduction in the Tpe interval and Tpe / QT ratio after TAVI was found to be significantly correlated with NLR (r=0.400, p=0.007; r=0.396, p=0.008; respectively).Conclusion: TAVI does not only reduce symptoms in patients with severe AS, but may also be effective in reducing risk of VA by improving factors affecting ventricular repolarization.
Açıklama
Anahtar Kelimeler
Kaynak
Annals of Medical Research
WoS Q Değeri
Scopus Q Değeri
Cilt
Sayı
Künye
Kaya, H. (2021). The effect of transcatheter aortic valve implantation on ventricular repolarization indices and neutrophil-to-lymphocyte ratio . Annals of Medical Research
