Impact of vitamin D supplementation on the ocular surface in patients with vitamin d deficiency
| dc.contributor.author | Alakus, Mehmet Fuat | |
| dc.contributor.author | Oncul, Hasan | |
| dc.contributor.author | Yilmaz Oncul, Fatma | |
| dc.contributor.author | Dag, Umut | |
| dc.contributor.author | Arac, Esref | |
| dc.date.accessioned | 2022-03-14T08:34:57Z | |
| dc.date.available | 2022-03-14T08:34:57Z | |
| dc.date.issued | 2020 | |
| dc.department | İnönü Üniversitesi | en_US |
| dc.description.abstract | Aim: The aim of this study was to determine the effect of vitamin D (vit D) supplementation on the ocular surface parameters in patients with vit D deficiency.Material and Methods: In total, 63 patients with serum vit D deficiency were included. Patients were treated with an oral dose of 300.000 IU cholecalciferol. The ocular surface disease index (OSDI) questionnaire, fluorescein tears breakup time (FBUT), Oxford score, and Schirmer’s 1 test were performed for all patients. The data was obtained initially and at 4, 8, and 12 weeks after vit D supplementation.Results: Forty-nine of the patients were female and 14 were male. The mean age was 30.8±9.7 (18–58) years. All 63 patients came to the first follow-up, 57 patients came to the second follow-up, and 48 patients came to the third follow-up. The OSDI and Oxford scores yielded statistically significant decreases, while Schirmer’s 1 test and FBUT values showed a statistically significant increase after treatment with vit D. A positive correlation was observed between vit D values and FBUT and Schirmer’s 1 values; there was a negative correlation between OSDI values (r=0.286 and p0.001, r=0.219 and p=0.032, r = -0.357 and p0.001, respectively). The dry eye findings improved significantly after vit D supplementation in all cases. Conclusion: During clinical follow-up, it is important to evaluate serum vit D levels in patients with dry eye syndrome (DES). Increasing their vit D levels will help clinicians to treat DES quickly and effectively. | en_US |
| dc.identifier.citation | Oncul, H., Fuat Alakus, M., Caglayan, M., Yilmaz Oncul, F., Dag, U., & Arac, E. (2021). Impact of vitamin D supplementation on the ocular surface in patients with vitamin d deficiency . Annals of Medical Research | en_US |
| dc.identifier.uri | https://hdl.handle.net/11616/55248 | |
| dc.language.iso | en | en_US |
| dc.relation.ispartof | Annals of Medical Research | en_US |
| dc.rights | info:eu-repo/semantics/openAccess | en_US |
| dc.title | Impact of vitamin D supplementation on the ocular surface in patients with vitamin d deficiency | en_US |
| dc.type | Article | en_US |
