Red and White Thrombus Characteristics in Patients Undergoing Carotid Endarterectomy

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dc.authoridKablan, Yüksel/0000-0002-5581-2968
dc.authoridAlan, Saadet/0000-0003-2329-151X
dc.authoridKamisli, Suat/0000-0003-4281-3301
dc.authorwosidKablan, Yüksel/AAB-5049-2021
dc.authorwosidKamisli, Suat/JZT-8388-2024
dc.authorwosidAlan, Saadet/ABH-4282-2020
dc.contributor.authorTosun, Hatice
dc.contributor.authorKamisli, Suat
dc.contributor.authorTecellioglu, Mehmet
dc.contributor.authorAlan, Saadet
dc.contributor.authorTecellioglu, Fahriye Secil
dc.contributor.authorOztanir, Mustafa Namik
dc.contributor.authorKablan, Yuksel
dc.date.accessioned2024-08-04T20:49:06Z
dc.date.available2024-08-04T20:49:06Z
dc.date.issued2021
dc.departmentİnönü Üniversitesien_US
dc.description.abstractObjective: The study aimed to compare the characteristics of red and white thrombi in patients undergoing carotid endarterectomy. Material and Methods: The study was conducted in 81 patients with ischemic stroke who underwent carotid endarterectomy for carotid artery stenosis. Carotid plaques were graded by two pathologists. Thrombus materials were divided into two groups: white and red. The parameters of assessment were plaque rupture, lipid core, fibrous cap thickness, inflammation, intraplaque hemorrhage, calcification, necrotic core, and neovascularization. Normally distributed data were evaluated using Mann-Whitney U and Chi-squared tests. Results: The ratio of white and red thrombus was 19.8% and 80.2%, respectively. Lipid core, plaque rupture, necrotic core, neovascularization, intraplaque hemorrhage, obstruction, and inflammation were observed more in red thrombus, which were statistically significant. Calcification and fibrous cap thickness were not statistically significant in the two groups. Moreover, intimal smooth muscle cells were present in all thrombus types. Conclusion: In our study, we found that red thrombi had more unstable characteristics than white thrombi. Thus, the risk for ischemic cerebrovascular events is more in red thrombi. However, this finding cannot be generalized due to the small number of patients in this study. Therefore, studies involving more patients are needed.en_US
dc.identifier.doi10.1016/j.jstrokecerebrovasdis.2020.105451
dc.identifier.issn1052-3057
dc.identifier.issn1532-8511
dc.identifier.issue2en_US
dc.identifier.pmid33278805en_US
dc.identifier.scopus2-s2.0-85097152784en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.urihttps://doi.org/10.1016/j.jstrokecerebrovasdis.2020.105451
dc.identifier.urihttps://hdl.handle.net/11616/99656
dc.identifier.volume30en_US
dc.identifier.wosWOS:000608421600051en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherElsevieren_US
dc.relation.ispartofJournal of Stroke & Cerebrovascular Diseasesen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectFibrous cap thicknessen_US
dc.subjectCarotid plaqueen_US
dc.subjectPlaque ruptureen_US
dc.subjectLipid coreen_US
dc.titleRed and White Thrombus Characteristics in Patients Undergoing Carotid Endarterectomyen_US
dc.typeArticleen_US

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