Evaluation of frontal QRS-T angle values in electrocardiography in patients with chronic rhinosinusitis

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dc.authorwosidabus, sabri/HKE-1420-2023
dc.contributor.authorAbus, Sabri
dc.contributor.authorKoparal, Mehtap
dc.contributor.authorKaya, Hakan
dc.contributor.authorKapici, Olga Bayar
dc.contributor.authorTasolar, Mehmet Hakan
dc.contributor.authorTibilli, Hakan
dc.date.accessioned2024-08-04T20:53:33Z
dc.date.available2024-08-04T20:53:33Z
dc.date.issued2023
dc.departmentİnönü Üniversitesien_US
dc.description.abstractBackgroundChronic Rhinosinusitis (CRS) refers to inflammation of the paranasal sinuses and nasal mucosa. Electrocardiographic indicators of ventricular repolarization have been shown to correlate with systemic inflammation parameters. Recently, the frontal QRS-T (fQRS-T) angle has been accepted as a new indicator of ventricular depolarization and repolarization heterogeneity. The (fQRS-T) angle is recommended in predicting the risk of malignant ventricular arrhythmia. In this study, we aimed to evaluate the ventricular arrhythmia potential in patients with chronic rhinosinusitis by examining the relationship between fQRS-T angle on ECG and inflammation markers.MethodsInflammatory markers as well as electrocardiographc (ECG) f(QRS-T) angle, QRS duration, QT interval and corrected QT interval were examined in 54 patients with CRS versus 56 healthy control subjects.ResultsThe f(QRS-T) angle was significantly higher in CRS patients than in healthy controls (p < .001). The neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR) and monocyte-to-lymphocyte ratio (MLR) were significantly higher in CRS patients compared to healthy controls (p < .001, for all). Based on correlation analysis, NLR and f(QRS-T) angles were highly correlated (r = .845, p < .001), and according to the results of linear regression analysis, NLR was independently associated with the f(QRS-T) angle (t = 5.149, Beta = 0.595, p = < 0.001).ConclusionBoth f(QRS-T) angle and NLR are significantly increased in CRS patients compared to healthy controls, with increases in NLR also independently associating with increases in f(QRS-T) angle. While the increases in f(QRS-T) angle did not result in clinically alarming absolute values for f(QRS-T), CRS patients might nonetheless be at relatively higher risk for malignant cardiac arrhythmias.en_US
dc.identifier.doi10.1186/s12872-023-03175-1
dc.identifier.issn1471-2261
dc.identifier.issue1en_US
dc.identifier.pmid36973652en_US
dc.identifier.scopus2-s2.0-85151000251en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.urihttps://doi.org/10.1186/s12872-023-03175-1
dc.identifier.urihttps://hdl.handle.net/11616/101253
dc.identifier.volume23en_US
dc.identifier.wosWOS:000957544800003en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherBmcen_US
dc.relation.ispartofBmc Cardiovascular Disordersen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectChronic rhinosinusitisen_US
dc.subjectNeutrophil to lymphocyte ratioen_US
dc.subjectFrontal QRS-T angleen_US
dc.titleEvaluation of frontal QRS-T angle values in electrocardiography in patients with chronic rhinosinusitisen_US
dc.typeArticleen_US

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