How safe is the use of herbal weight-loss products sold over the Internet?

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dc.authoriderdogan, selim/0000-0002-9169-9771
dc.authoridÖnal, Yunus/0000-0001-6342-6816;
dc.authorwosiderdogan, selim/AAT-2487-2020
dc.authorwosidÖnal, Yunus/E-7170-2018
dc.authorwosidCelbiş, Osman/ABE-2803-2021
dc.authorwosidOzdemir, Bora/B-6655-2013
dc.contributor.authorOzdemir, B.
dc.contributor.authorSahin, I.
dc.contributor.authorKapucu, H.
dc.contributor.authorCelbis, O.
dc.contributor.authorKarakoc, Y.
dc.contributor.authorErdogan, S.
dc.contributor.authorOnal, Y.
dc.date.accessioned2024-08-04T20:37:22Z
dc.date.available2024-08-04T20:37:22Z
dc.date.issued2013
dc.departmentİnönü Üniversitesien_US
dc.description.abstractBackground: In recent years, the use of herbal weight-loss products sold over the Internet has rapidly increased; however, the safety of these products has not been well documented yet. More importantly, the declared ingredients in these products could be different than the marketed contents. Methods: Nine different herbal weight-loss products sold over the Internet were obtained. The ingredients of each product were analyzed in the Laboratory of Forensic Medicine and the Scientific and Technological Research Laboratory of Inonu University. Results: Although all studied weight-loss products were presented as pure herbal, three of them contain sibutramine, three contain caffeine, and three contain caffeine + temazepam. The amount of sibutramine in each capsule was found to be over 10 mg. We analyzed toxic and trace element levels of nine herbal products and found that these herbal products, even in low amounts, contain Pb, Al, Ni, and Ba. Conclusions: Our results indicate that herbal weight-loss products available without prescription and claimed to be purely herbal may contain pharmaceutical substances like sibutramine or temazepam in high doses. Moreover, they also may become contaminated with toxic metals. Since people commonly use these products unaware of its real constituents and without the suggestion or control of a physician, they might cause various health problems some of which might be harmful. Strict legal rules and control mechanisms must be established to minimize their possible harmful effects.en_US
dc.identifier.doi10.1177/0960327112436407
dc.identifier.endpage106en_US
dc.identifier.issn0960-3271
dc.identifier.issn1477-0903
dc.identifier.issue1en_US
dc.identifier.pmid22354083en_US
dc.identifier.scopus2-s2.0-84871563747en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage101en_US
dc.identifier.urihttps://doi.org/10.1177/0960327112436407
dc.identifier.urihttps://hdl.handle.net/11616/95896
dc.identifier.volume32en_US
dc.identifier.wosWOS:000312692600011en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherSage Publications Ltden_US
dc.relation.ispartofHuman & Experimental Toxicologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectadulterationen_US
dc.subjectcontaminationen_US
dc.subjecttoxic metalsen_US
dc.subjecttrace elementsen_US
dc.subjectweight lossen_US
dc.subjectherbal productsen_US
dc.titleHow safe is the use of herbal weight-loss products sold over the Internet?en_US
dc.typeArticleen_US

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