Risk factors for 30-day mortality in patients with cancer and COVID-19 in Turkey: A single center retrospective study
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Tarih
2022
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info:eu-repo/semantics/openAccess
Özet
Aim: We aimed to investigate the factors affecting mortality in cancer patients with COVID-19.
Materials and Methods: 120 cancer patients followed-up in Erciyes University Medical Oncology Department were included in the study. Patients with a diagnosed cancer over the age of 18 years and diagnosis of COVID-19 between April 1 and December 1 2020 were participated in the study. The relationship between clinical, demographic, laboratory values and 30-day mortality were evaluated using the Chi-square and Fisher's exact test. Risk factors for mortality were identified by univariable and multivariable logistic regression models.
Results: 120 cancer patients were accepted in the study and 30 (25%) had died within 30 days after COVID-19 positivity. Hospitalization rate of cancer patients with COVID-19 was 67.5% and 23 (19.2%) of patients were admitted to intensive care unit (ICU). 34.6% of hospitalized patients and 95.7% of those admitted in the ICU died within 30 days. In multivariable logistic regression analysis, it was concluded that the presence of lymphopenia (OR 2.2, 95% CI 1.54-13.6, p = 0.04), high neutrophil-lymphocyte ratio (NLR) (OR 3.1, 95% CI 1.21-9.8, p = 0.02), dyspnea (OR 2.5 95% CI 0.32-11.2, p = 0.04), lung cancer diagnoses (OR 3.3 95% CI 1.54-9.7, p = 0.03), male gender (OR 2.17 95% CI 1.1-7.3, p = 0.03) ) were determined that increased 30-day mortality.
Conclusion: High incidence of cancer and the risk of immunosuppression in these patients increased the importance of COVID-19. Cancer patients with COVID-19 need to be treated more carefully because they are vulnerable to infection and can be mortal.
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Annals of Medical Research
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Mutlu, E., Firat, S. T., Inanc, M., Bozkurt, O., Cosar, R., & Ozkan, M. (2022). Risk factors for 30-day mortality in patients with cancer and COVID-19 in Turkey: A single center retrospective study. Annals of Medical Research
