Tunable and tough porous chitosan/?-cyclodextrin/tannic acid biocomposite membrane with mechanic, antioxidant, and antimicrobial properties

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dc.authoridAteş, Burhan/0000-0001-6080-229X
dc.authoridUlu, Ahmet/0000-0002-4447-6233
dc.authorwosidAteş, Burhan/AAA-3730-2021
dc.authorwosidUlu, Ahmet/L-5180-2016
dc.contributor.authorUlu, Ahmet
dc.contributor.authorBirhanli, Emre
dc.contributor.authorAtes, Burhan
dc.date.accessioned2024-08-04T20:50:33Z
dc.date.available2024-08-04T20:50:33Z
dc.date.issued2021
dc.departmentİnönü Üniversitesien_US
dc.description.abstractHerein, tannic acid (TA)-reinforced chitosan (CHS)/beta-cyclodextrin (beta-CD) biocomposite membranes were prepared by TA solution incubating treatment. The functional groups, crystal structure, and morphological characterizations of the prepared biocomposite membranes were investigated using various methods. The biocomposite membranes were investigated in terms of their wettability, porosity, swelling degree, and water uptake. In vitro antioxidant investigation was carried out through DPPH assay. Moreover, the prepared biocomposite membranes were evaluated for their antimicrobial ability against three different microbial species. The introduction of TA effectively improved the swelling behavior, mechanical strength, and porosity of the biocomposite membranes. TA increased the tensile strength from 0.7 +/- 0.2 MPa to a maximum of 2.2 +/- 0.6 MPa and elongation at break from 26.9 +/- 0.7% to a maximum of 36.7 +/- 3.5%. The biocomposite membranes showed an initial burst release of TA (similar to 40%) within 6 h, followed by a gradual release of 100% by 18 h. Furthermore, the introduction of TA into the biocomposite membranes further improved the antimicrobial activities against both bacteria and yeast, as well as the in vitro antioxidant potential. As a consequence, the prepared biocomposite membranes could potentially be used as scaffold in broaden biomedical fields due to their adaptable structure, porosity, greatly antioxidant, and antimicrobial activity.en_US
dc.identifier.doi10.1016/j.ijbiomac.2021.08.068
dc.identifier.endpage707en_US
dc.identifier.issn0141-8130
dc.identifier.issn1879-0003
dc.identifier.pmid34400232en_US
dc.identifier.scopus2-s2.0-85112748285en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage696en_US
dc.identifier.urihttps://doi.org/10.1016/j.ijbiomac.2021.08.068
dc.identifier.urihttps://hdl.handle.net/11616/100137
dc.identifier.volume188en_US
dc.identifier.wosWOS:000697936100006en_US
dc.identifier.wosqualityQ1en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherElsevieren_US
dc.relation.ispartofInternational Journal of Biological Macromoleculesen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectChitosanen_US
dc.subjectTannic aciden_US
dc.subjectbeta-Cyclodextrinen_US
dc.subjectBiocompositeen_US
dc.subjectAntioxidanten_US
dc.subjectAntimicrobial activityen_US
dc.titleTunable and tough porous chitosan/?-cyclodextrin/tannic acid biocomposite membrane with mechanic, antioxidant, and antimicrobial propertiesen_US
dc.typeArticleen_US

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