Effects of preemptive intravenous paracetamol and ibuprofen on headache and myalgia in patients after electroconvulsive therapy A placebo-controlled, double-blind, randomized clinical trial

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dc.authoridOzkan, Ahmet Selim/0000-0002-4543-8853
dc.authoridZayman, Esra Porgalı/0000-0003-1551-6782
dc.authoridAkbas, Sedat/0000-0003-3055-9334
dc.authoridkaraaslan, erol/0000-0002-8534-3680
dc.authorwosidOzkan, Ahmet Selim/ABH-2918-2020
dc.authorwosidZayman, Esra Porgalı/ABI-2950-2020
dc.authorwosidAkbas, Sedat/ABI-6053-2020
dc.authorwosidkaraaslan, erol/ABI-2700-2020
dc.contributor.authorKaraaslan, Erol
dc.contributor.authorAkbas, Sedat
dc.contributor.authorOzkan, Ahmet Selim
dc.contributor.authorZayman, Esra Porgali
dc.date.accessioned2024-08-04T20:47:03Z
dc.date.available2024-08-04T20:47:03Z
dc.date.issued2019
dc.departmentİnönü Üniversitesien_US
dc.description.abstractBackground: The aim of this study is to determine the efficacy of preemptive analgesia with paracetamol and ibuprofen to reduce the intensity and incidence of headache and myalgia after electroconvulsive therapy (ECT). Methods: Sixty patients with major depression who were treated with ECT were randomized to receive ECT 3 times a week. The first 3 sessions were included in the study. The patients were divided into 3 groups; Group C (Control, Saline, n = 20), Group P (Paracetamol, n = 20), and Group I (Ibuprofen, n = 20). Demographics, duration of seizure, visual analog scale (VAS) for headache and myalgia and nausea, vomiting and pruritus were evaluated at postoperative 24 hours period. Results: Duration of seizure after ECT was similar in all groups (P=.148). In the study, heart rate and mean arterial pressure were found to be some changes in some of the sessions. There were no significant differences in any comparison for all groups in all sessions regarding VAS scores for headache and myalgia. Incidence of headache and myalgia in Group I was lower than the other groups (P=.233, P=.011, respectively). But, there was no significant difference between the other groups. There was no significant difference in vomiting, intergroups, and intragroup. Conclusions: The findings of our study indicate that pain intensity of headache and myalgia did not show a significant change between groups and within groups. While pain intensity of myalgia between the groups reached no statistical significance, ibuprofen was significantly lowered the incidence of myalgia at postoperative 24 hours period.en_US
dc.description.sponsorshipInonu University Coordination Unit of Scientific research projects [TSA-2018-1067]en_US
dc.description.sponsorshipThis study was supported by the Inonu University Coordination Unit of Scientific research projects (Project no: TSA-2018-1067).en_US
dc.identifier.doi10.1097/MD.0000000000018473
dc.identifier.issn0025-7974
dc.identifier.issn1536-5964
dc.identifier.issue51en_US
dc.identifier.pmid31861028en_US
dc.identifier.scopus2-s2.0-85077008719en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.urihttps://doi.org/10.1097/MD.0000000000018473
dc.identifier.urihttps://hdl.handle.net/11616/99116
dc.identifier.volume98en_US
dc.identifier.wosWOS:000511458900086en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherLippincott Williams & Wilkinsen_US
dc.relation.ispartofMedicineen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectelectroconvulsive therapyen_US
dc.subjectheadacheen_US
dc.subjectibuprofenen_US
dc.subjectmyalgiaen_US
dc.subjectparacetamolen_US
dc.titleEffects of preemptive intravenous paracetamol and ibuprofen on headache and myalgia in patients after electroconvulsive therapy A placebo-controlled, double-blind, randomized clinical trialen_US
dc.typeArticleen_US

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