Thromboelastographic comparison of the effects of different fluid preloading regimens delivered before spinal anesthesia

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dc.authoridToprak, Hüseyin İlksen/0000-0001-9293-8116
dc.authoridErsoy, Mehmet/0000-0002-0724-2825
dc.authoridaydogan, mustafa said/0000-0002-7106-1156
dc.authoridGulhas, Nurcin/0000-0002-2539-9017
dc.authorwosidToprak, Hüseyin İlksen/AAN-4023-2020
dc.authorwosidErsoy, Mehmet/ACN-2779-2022
dc.authorwosidaydogan, mustafa said/AAA-2828-2021
dc.authorwosidErdogan, Mehmet Ali/ABI-7224-2020
dc.authorwosidGulhas, Nurcin/A-7281-2018
dc.contributor.authorOzen, Irsat
dc.contributor.authorTogal, Turkan
dc.contributor.authorAydogan, Mustafa Said
dc.contributor.authorErdogan, Mehmet Ali
dc.contributor.authorNakir, Hamza
dc.contributor.authorGulhas, Nurcin
dc.contributor.authorToprak, Huseyin Ilksen
dc.date.accessioned2024-08-04T20:36:16Z
dc.date.available2024-08-04T20:36:16Z
dc.date.issued2012
dc.departmentİnönü Üniversitesien_US
dc.description.abstractIntroduction: Various fluids used for preloading purposes prior to spinal anesthesia. Coagulation disorders can occur due to use of those fluids at large volumes [1]. We aimed to compare the impact of different preloading fluids over coagulation parameters. Method: Sixty-eight patients of ASA I-II physical status who were aged between 18 and 75 years, and scheduled for orthopedic surgery under spinal anesthesia, were included in the study. Prior to the spinal anesthesia, preloading was carried out by RL in Group R (n=16), HES (130/0.4) in Group H (n=16), polygeline in Group P (n=16), and succinylated gelatin 7 ml/kg in Group S (n=16). RL was used as the maintenance fluid in all the groups. Thromboelastography, CBC, PTT, aPTT, fibrinogen values were assessed at baseline and 2 hours. Results: Groups P and S displayed significantly prolonged PTT values. While Groups R and P showed significantly prolonged PTT-INR values, groups R and H exhibited significantly prolonged aPTT values. Groups R, P, and S demonstrated significant decreases in TEG parameters including R, K, CI, and TMA. The increase in a angle was significant in groups R and S. Conclusion: Fluid preloading with HES was not found to affect the coagulation parameters, however, polygeline and succinylated gelatin were observed to cause moderate hypercoagulation. Therefore, we believe that HES may be preferred over succinylated gelatin and polygeline in cases with hypercoagulability.en_US
dc.identifier.endpage3493en_US
dc.identifier.issn1840-2291
dc.identifier.issn1986-8103
dc.identifier.issue10en_US
dc.identifier.scopus2-s2.0-84871252188en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage3488en_US
dc.identifier.urihttps://hdl.handle.net/11616/95890
dc.identifier.volume6en_US
dc.identifier.wosWOS:000312158300037en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherDrunpp-Sarajevoen_US
dc.relation.ispartofHealthmeden_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectHypercoagulabilityen_US
dc.subjectthromboelastographyen_US
dc.subjectpreloading fluiden_US
dc.subjectspinal anesthesiaen_US
dc.titleThromboelastographic comparison of the effects of different fluid preloading regimens delivered before spinal anesthesiaen_US
dc.typeArticleen_US

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