In vitro antimicrobial studies of new benzimidazolium salts and silver N-heterocyclic carbene complexes

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dc.authoridAlbayrak, Sevil/0000-0002-0253-3746
dc.authoridAkkoc, Senem/0000-0002-1260-9425
dc.authorwosidAkkoç, Senem/AAN-1478-2021
dc.authorwosidGök, Yetkin/AAA-5669-2021
dc.authorwosidAlbayrak, Sevil/AAA-2308-2021
dc.contributor.authorGok, Yetkin
dc.contributor.authorAkkoc, Senem
dc.contributor.authorErdogan, Hulya
dc.contributor.authorAlbayrak, Sevil
dc.date.accessioned2024-08-04T20:41:26Z
dc.date.available2024-08-04T20:41:26Z
dc.date.issued2016
dc.departmentİnönü Üniversitesien_US
dc.description.abstractA series of new benzimidazolium salts (1a-g) were synthesized from the reaction of 1-(4-vinylbenzyl) benzimidazole with various alkyl halides. These salts were used to synthesize silver N-heterocyclic carbene (Ag-NHC) complexes (2a-f). The thirteen compounds were characterized by FT-IR, NMR (H-1 and C-13) spectroscopic methods and an elemental analysis technique. These selected candidates were tested for their in vitro antimicrobial activities. Antibacterial and antifungal results indicated that the new salts, and particularly their silver complexes, were found to be strongly effective against seven Gram (-) bacterial strains, three Gram (+) bacterial strains and one yeast (Candida albicans).en_US
dc.description.sponsorshipInonu University Research Fund [I.U.B.A.P. 2012/02]en_US
dc.description.sponsorshipThis work was financially supported by Inonu University Research Fund (I.U.B.A.P. 2012/02).en_US
dc.identifier.doi10.3109/14756366.2015.1132210
dc.identifier.endpage1327en_US
dc.identifier.issn1475-6366
dc.identifier.issn1475-6374
dc.identifier.issue6en_US
dc.identifier.pmid26744769en_US
dc.identifier.scopus2-s2.0-84953775719en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage1322en_US
dc.identifier.urihttps://doi.org/10.3109/14756366.2015.1132210
dc.identifier.urihttps://hdl.handle.net/11616/97106
dc.identifier.volume31en_US
dc.identifier.wosWOS:000385270300058en_US
dc.identifier.wosqualityQ1en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherTaylor & Francis Ltden_US
dc.relation.ispartofJournal of Enzyme Inhibition and Medicinal Chemistryen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectAntimicrobial activityen_US
dc.subjectbenzimidazolium salten_US
dc.subjectN-heterocyclic carbeneen_US
dc.subjectsilver complexen_US
dc.titleIn vitro antimicrobial studies of new benzimidazolium salts and silver N-heterocyclic carbene complexesen_US
dc.typeArticleen_US

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