Protective effect of dietary apricot kernel oil supplementation on cholesterol levels and antioxidant status of liver in hypercholesteremic rats

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dc.authoridKUTLU, Turkan/0000-0002-1501-9930
dc.authoridDurmaz, Gökhan/0000-0003-3423-8108
dc.authoridAteş, Burhan/0000-0001-6080-229X
dc.authorwosidERDOĞAN, Ali/ABG-8548-2020
dc.authorwosidKUTLU, Turkan/ABI-2589-2020
dc.authorwosidDurmaz, Gökhan/E-7121-2016
dc.authorwosidAteş, Burhan/AAA-3730-2021
dc.contributor.authorKutlu, Tuerkan
dc.contributor.authorDurmaz, Goekhan
dc.contributor.authorAtes, Burhan
dc.contributor.authorErdogan, Ali
dc.date.accessioned2024-08-04T20:32:14Z
dc.date.available2024-08-04T20:32:14Z
dc.date.issued2009
dc.departmentİnönü Üniversitesien_US
dc.description.abstractApricot kernel oil is a rich source of MUFA and PUFA, including mainly oleic (about 70%) and linoleic acids, respectively. In addition, apricot kernel oil could be considered as a good source of bioactive compounds such as tocopherols and phytosterols consisting mainly of they gamma-isomer and beta-sitosterol, respectively. Given to its high content of oleic acid, apricot kernel oil is considered as a healthy supplement in diet. In the present study, we investigated the effects of apricot kernel oil supplementation on cholesterol and malondialdehyde (MDA) levels and glutathione peroxidase (GPx) and catalase (CAT) activity in hypercholesteremic rats. Hypercholesteremia was produced by feeding rats with a semisynthetic diet that contained high cholesterol and cholic acid. A high cholesterol diet caused a decrease in CAT and GPx activity, while apricot kernel oil caused a significant activity increase of these enzymes (P < 0.05). The group fed with apricot kernel oil supplementation showed higher enzyme activities than sunflower oil groups irrespective of cholesterol (P < 0.05). Results of the present study indicate that apricot kernel oil causes improvement in liver antioxidant status of rats in comparison to sunflower oil which is a commonly consumed vegetable oil.en_US
dc.description.sponsorshipInonu University Scientific Project Unit [BAP/2004-10]en_US
dc.description.sponsorshipThis research was supported by Inonu University Scientific Project Unit (BAP/2004-10). We would like to thank Dr. Hikmet Geckil (Inonu University, Faculty of Sciences & Arts, Department of Biology, Turkey) and Dr. Kazim Sahin (Firat University, Faculty of Veterinary Science, Department of Animal Nutrition, Turkey) for his critical reading of the manuscript.en_US
dc.identifier.endpage65en_US
dc.identifier.issn1459-0255
dc.identifier.issn1459-0263
dc.identifier.issue3-4en_US
dc.identifier.scopus2-s2.0-73949149921en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage61en_US
dc.identifier.urihttps://hdl.handle.net/11616/94950
dc.identifier.volume7en_US
dc.identifier.wosWOS:000272054400012en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherWfl Publen_US
dc.relation.ispartofJournal of Food Agriculture & Environmenten_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectApricot kernel oilen_US
dc.subjectcholesterolen_US
dc.subjectsunflower oilen_US
dc.subjectmalondialdehydeen_US
dc.subjectcatalaseen_US
dc.subjectglutathione peroxidaseen_US
dc.titleProtective effect of dietary apricot kernel oil supplementation on cholesterol levels and antioxidant status of liver in hypercholesteremic ratsen_US
dc.typeArticleen_US

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