Evaluation of the relationship of the time of vesicoureteral reflux between renal scar development and endoscopic treatment success in early childhood

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dc.contributor.authorTaşolar, Sevgi
dc.contributor.authorSığırcı, Ahmet
dc.contributor.authorDoğan, Güleç Mert
dc.contributor.authorCengiz, Aslınur
dc.contributor.authorYıldız, Turan
dc.contributor.authorSubaşı, Vedat
dc.contributor.authorTabel, Yılmaz
dc.date.accessioned2024-08-04T19:42:42Z
dc.date.available2024-08-04T19:42:42Z
dc.date.issued2022
dc.departmentİnönü Üniversitesien_US
dc.description.abstractAim: It is aimed to evaluate the effect of reflux time in primary VUR in terms of predicting endoscopic treatment success and treatment timing in VUR management. Vesicoureteral reflux (VUR) is an important cause of urinary tract infection and chronic renal disease. Voiding cystourethrography (VCUG) is the gold standard diagnostic test in the diagnosis of VUR. In recent years, new parameters related to VCUG have been more objectively studied to evaluate the clinical prognosis. Materials and Methods: In our study, the records and imaging findings of children with primary VUR who underwent VCUG examination between 2012 and 2019, who were treated with endoscopic injections, were retrospectively reviewed. Forty-one children (67 renal units) were included in our study. Patients with preoperative VCUG, urinary ultrasonography, dimercaptosuccinic acid (DMSA) renal scan, and post-operative control VCUG were included in this study. Results: Patients with preoperative VUR grade 1-2 were divided into two groups as “low grade” and patients with stage 3-4-5 as “high grade”. In the general patient pop- ulation, endoscopic success rates in terms of renal unit deficit were found to be 46.3% (31/67). When the subgroup was analyzed, the endoscopic treatment success rate was 72.2% (13/18) in the low-grade group, versus 36.7% (18/49) in the high-grade group (p = 0.010). In the multivariate logistic regression analysis performed to identify indepen- dent predictors of scarring, reflux degree and reflux time were found to be independent predictors of scarring. Conclusion: In our study, we found that in VCUG evaluated preoperatively, VUR time as well as VUR grade were effective on endoscopic success rate and scar development. Based on these results, it could be thought that VUR time may be effective in selecting the best candidates for surgery and in the management and timing of treatment of VUR patients.en_US
dc.identifier.doi10.5455/annalsmedres.2022.03.083
dc.identifier.endpage878en_US
dc.identifier.issn2636-7688
dc.identifier.issue8en_US
dc.identifier.startpage874en_US
dc.identifier.trdizinid1126856en_US
dc.identifier.urihttps://doi.org/10.5455/annalsmedres.2022.03.083
dc.identifier.urihttps://search.trdizin.gov.tr/yayin/detay/1126856
dc.identifier.urihttps://hdl.handle.net/11616/88576
dc.identifier.volume29en_US
dc.indekslendigikaynakTR-Dizinen_US
dc.language.isoenen_US
dc.relation.ispartofAnnals of Medical Researchen_US
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.titleEvaluation of the relationship of the time of vesicoureteral reflux between renal scar development and endoscopic treatment success in early childhooden_US
dc.typeArticleen_US

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