Aile içinde hepatit b virüsünün geçişi
Yükleniyor...
Dosyalar
Tarih
1997
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
İnönü Üniversitesi Tıp Fakültesi Dergisi
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Aile içinde hepatit B virımı geçişini araştırmak amacıyla kliniğimize başvuran kronik HBsAg taşıyıcı ve kronik hepatitli 82 olgu ’mm aile bireyleri hepatit B göstergeleri yönünden araştırıldı. 184 aile bireyinin serumları ELISA yöntemi ile tarandı. Kontrol grubu olarak herhangi bir şikayeti olmayan ve risk grubunda bulunmayan 75 kişi alındı ve aynı yöntemle hepatit B göstergelerine bakıldı. Aile bireylerinde HBsAg pozitifliği %16.5, anti HBsAg pozitifliği %17.6 ve toplam seropozitivite %34.1 bulunurken kontrol grubunda HBsAg %5.3, antiHBsAg %6.6 ve toplam serpozitivite %11.9 olarak bulundu. İki grup arasındaki fark istatistiksel olarak anlamlı idi (p<0.05). Aile bireylerinde seropozitivitenin yüksekliği ve kardeşler arasında da geçişin yüksek olması perinatal geçiş yanında horizontal geçişin düşünülmesi gerektiğini desteklemiştir. Sonuç olarak aile bireyleri risk grubundadır ve HBsAg taşıyıcıların aile bireyleri taranmalı ve hepatit B virusu yönünde proflaksi uygulanmalıdır.
To investigate the transmission of hepatitis B virus in family, we researched hepatit B markers in families of 82 chronic HBsAg carriers. The serums of 182 family members were searched with ELISA technique. We took a control group 75 people without any complaint and in an any risk group. In family members, HBsAg positivity was 16.5%, anti HBs positivity was 17.6%, and total sero-positivity was 34.1%, while in control group, HBsAg was 5.3%, anti HBs was 6.6%, and total sero-positivity was 11.9%. The difference between the two groups was statistically significant (p<0.05). High sero-positivity and high transmission in family members and high transmission between siblings support that horizontal transmission in addition to perinatal transmission must be considered in hepatitis B. As a result the family members have a risk for hepatitis B and family members of HBsAg carriers must be checked and vaccinated.
To investigate the transmission of hepatitis B virus in family, we researched hepatit B markers in families of 82 chronic HBsAg carriers. The serums of 182 family members were searched with ELISA technique. We took a control group 75 people without any complaint and in an any risk group. In family members, HBsAg positivity was 16.5%, anti HBs positivity was 17.6%, and total sero-positivity was 34.1%, while in control group, HBsAg was 5.3%, anti HBs was 6.6%, and total sero-positivity was 11.9%. The difference between the two groups was statistically significant (p<0.05). High sero-positivity and high transmission in family members and high transmission between siblings support that horizontal transmission in addition to perinatal transmission must be considered in hepatitis B. As a result the family members have a risk for hepatitis B and family members of HBsAg carriers must be checked and vaccinated.
Açıklama
[Journal of Turgut Ozal Medical Center 1997;4(4):430-433]
Anahtar Kelimeler
Hepatit B, Ailesel geçiş, İntrafamilial transmission
Kaynak
Turgut Özal Tıp Merkezi Dergisi
WoS Q Değeri
Scopus Q Değeri
Cilt
4
Sayı
4
Künye
Ersoy, Y.,Sönmez, E.,Çetin, C.,Durmaz, R.,(1997). Aile içinde hepatit b virüsünün geçişi.Turgut Özal Tıp Merkezi Dergisi, 4 (4).430-433 ss.
