Histopathological effects of fibrin glue on penile fracture in a rat model

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dc.authoridTurtay, Muhammet Gokhan/0000-0002-1728-8237
dc.authoridTurkmen, Samdanci, Emine/0000-0002-0034-5186
dc.authoridOguzturk, Hakan/0000-0002-9800-1428
dc.authoridOzdemir, Hulya/0000-0002-9435-9596
dc.authorwosidTurtay, Muhammet Gokhan/ABG-7401-2020
dc.authorwosidTurkmen, Samdanci, Emine/ABH-4716-2020
dc.authorwosidOguzturk, Hakan/AAC-3915-2021
dc.authorwosidFirat, Cemal/D-1292-2012
dc.authorwosidoguzturk, hakan/Q-6242-2019
dc.contributor.authorTasdemir, Cemal
dc.contributor.authorSamdanci, Emine T.
dc.contributor.authorTurtay, Muhammet G.
dc.contributor.authorFirat, Cemal
dc.contributor.authorOguzturk, Hakan
dc.contributor.authorOzdemir, Hulya
dc.date.accessioned2024-08-04T20:35:50Z
dc.date.available2024-08-04T20:35:50Z
dc.date.issued2011
dc.departmentİnönü Üniversitesien_US
dc.description.abstractPurpose: To evaluate both histopathological effects and potential clinical application of fibrin glue on the penile cavernosal tissue. Methods: Experimental penile fracture was formed by incising from the proximal dorsal side of the penis in 32 Wistar Albino rats. The rats were randomly assigned to four main groups of eight animals each. In the control group, the incision was not repaired and it was left to secondary healing. In the primary repair group, the incision was primarily repaired. In the fibrin glue group, glue was applied only to the incision. In the final group, fibrin glue was applied to the incision following primary repair. Three weeks later, penectomy tissue was examined histopathologically. Results: When the control group was compared with primary repair+fibrin glue group, the differences in cavernous tissue healing with fibrosis and inflammation were statistically significant (p = 0.04 and 0.01, respectively). The primary repair+fibrin glue group, showed the best cavernous healing with fibrosis observed in only one rat.. There was no significant difference between the control group and the other groups according to cavernous tissue healing with fibrosis and inflammation (p = 0.11 and 0.12). Hyperemia was observed in the all groups of rats. Conclusions: Fibrin glue can be used in cavernoseal surgeries due to its adhesive and potentially anti-inflammatory features.en_US
dc.identifier.endpageE340en_US
dc.identifier.issn0147-958X
dc.identifier.issn1488-2353
dc.identifier.issue6en_US
dc.identifier.pmid22129922en_US
dc.identifier.scopus2-s2.0-84858602825en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpageE336en_US
dc.identifier.urihttps://hdl.handle.net/11616/95600
dc.identifier.volume34en_US
dc.identifier.wosWOS:000297727400006en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherCanadian Soc Clinical Investigationen_US
dc.relation.ispartofClinical and Investigative Medicineen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectSealanten_US
dc.subjectExperienceen_US
dc.subjectRepairen_US
dc.subjectTissueen_US
dc.titleHistopathological effects of fibrin glue on penile fracture in a rat modelen_US
dc.typeArticleen_US

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