Synthesis and characterization of acrylamide-based copolymeric hydrogel-silver composites: Antimicrobial activities and inhibition kinetics against E-coli

dc.authoridBilenler, Tugca/0000-0001-7831-6337
dc.authoridBoztepe, Cihangir/0000-0001-5019-2010
dc.authoridTOSUN, Emir/0000-0002-2555-1840
dc.authorwosidBilenler, Tugca/ABG-8427-2020
dc.authorwosidBoztepe, Cihangir/H-5877-2018
dc.authorwosidŞişlioğlu, Kübra/W-4778-2018
dc.authorwosidTOSUN, Emir/S-5125-2018
dc.contributor.authorBoztepe, Cihangir
dc.contributor.authorTosun, Emir
dc.contributor.authorBilenler, Tugca
dc.contributor.authorSislioglu, Kubra
dc.date.accessioned2024-08-04T20:43:14Z
dc.date.available2024-08-04T20:43:14Z
dc.date.issued2017
dc.departmentİnönü Üniversitesien_US
dc.description.abstractA series of acrylamide (AAm)-based hydrogels containing acrylic acid, 2-acrylamido-2-methyl-1-propanesulfonic acid (AMPS), and vinyl imidazole (VI) comonomers were prepared by free radical polymerization. Silver nanoparticles were loaded to hydrogel systems through in situ reduction of silver nitrate in the presence of sodium borohydride as a reducing agent. The synthesized hydrogels and their composites were characterized using FTIR, scanning electron microscopy, EDX, and EDX-mapping. The antimicrobial activity of hydrogel-silver composite was determined using well agar and broth dilution tests. In the first stage, four different hydrogel-silver composites were evaluated against six different microorganisms using the well agar technique. The most effective hydrogel-silver composite among all tested was poly(AAm-co-VI-co-AMPS)-Ag, while the most sensitive and resistant microorganisms among all tested were Staphylococcus cerevisiae and S. aureus, respectively. Poly(AAm-co-VI-co-AMPS)-Ag composite was used in modeling the inhibition kinetic of Escherichia coli. The present study displays that hydrogel-silver composite has considerable antimicrobial activity, which deserves further investigation for use in clinic application and industrial processing. [GRAPHICS] .en_US
dc.identifier.doi10.1080/00914037.2017.1291513
dc.identifier.endpage942en_US
dc.identifier.issn0091-4037
dc.identifier.issn1563-535X
dc.identifier.issue18en_US
dc.identifier.scopus2-s2.0-85021779170en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage934en_US
dc.identifier.urihttps://doi.org/10.1080/00914037.2017.1291513
dc.identifier.urihttps://hdl.handle.net/11616/97877
dc.identifier.volume66en_US
dc.identifier.wosWOS:000416005800004en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherTaylor & Francis Asen_US
dc.relation.ispartofInternational Journal of Polymeric Materials and Polymeric Biomaterialsen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAcrylamide-based hydrogelsen_US
dc.subjectantimicrobial activityen_US
dc.subjecthydrogel-silver compositesen_US
dc.subjectinhibition kineticen_US
dc.titleSynthesis and characterization of acrylamide-based copolymeric hydrogel-silver composites: Antimicrobial activities and inhibition kinetics against E-colien_US
dc.typeArticleen_US

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