Evaluation of the Association of VDR rs2228570 Polymorphism with Elite Track and Field Athletes' Competitive Performance

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dc.authoridMijaica, Raluca/0000-0002-1071-8003
dc.authoridEken, Özgür/0000-0002-5488-3158
dc.authoridKazan, Hasan Huseyin/0000-0001-7936-8606
dc.authoridBAYRAKTAR, ISIK/0000-0003-1001-5348
dc.authoridGrosz, Wilhelm Robert/0000-0001-6241-5277
dc.authoridBULGAY, Celal/0000-0003-4026-9883
dc.authoridUlucan, Korkut/0000-0002-1304-9386
dc.authorwosidMijaica, Raluca/R-6531-2019
dc.authorwosidEken, Özgür/ABE-8274-2020
dc.authorwosidKazan, Hasan Huseyin/HSH-9265-2023
dc.authorwosidBAYRAKTAR, ISIK/KLC-9270-2024
dc.authorwosidergun, mehmet ali/AAW-4367-2021
dc.authorwosidCerit, Mesut/AAM-8885-2021
dc.authorwosidGrosz, Wilhelm Robert/G-6570-2016
dc.contributor.authorBulgay, Celal
dc.contributor.authorBayraktar, Isik
dc.contributor.authorKazan, Hasan Huseyin
dc.contributor.authorYildirim, Damla Selin
dc.contributor.authorZorba, Erdal
dc.contributor.authorAkman, Onur
dc.contributor.authorErgun, Mehmet Ali
dc.date.accessioned2024-08-04T20:53:31Z
dc.date.available2024-08-04T20:53:31Z
dc.date.issued2023
dc.departmentİnönü Üniversitesien_US
dc.description.abstractThe present study aimed to examine the vitamin D receptor (VDR), rs2228570 polymorphism, and its effect on elite athletes' performance. A total of 60 elite athletes (31 sprint/power and 29 endurance) and 20 control/ physically inactive, aged 18-35, voluntarily participated in the study. The International Association of Athletics Federations (IAAF) score scale was used to determine the performance levels of the athletes' personal best (PB). Whole exome sequencing (WES) was performed by the genomic DNA isolated from the peripheral blood of the participants. Sports type, sex, and competitive performance were chosen as the parameters to compare within and between the groups by linear regression models. The results showed no statistically significant difference between the CC, TC, and TT genotypes within and between the groups (p > 0.05). Additionally, our results underlined that there were no statistically significant differences for the association of rs2228570 polymorphism with PBs within the groups of the (p > 0.05) athletes. The genetic profile in the selected gene was similar in elite endurance, sprint athletes, and in controls, suggesting that rs2228570 polymorphism does not determine competitive performance in the analyzed athlete cohort.en_US
dc.description.sponsorshipGazi University Rectorate (Scientific Research Projects Coordination's Unit) [TCD-2021-7116]en_US
dc.description.sponsorshipThis research received no external funding.en_US
dc.identifier.doi10.3390/healthcare11050681
dc.identifier.issn2227-9032
dc.identifier.issue5en_US
dc.identifier.pmid36900688en_US
dc.identifier.scopus2-s2.0-85149708053en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.urihttps://doi.org/10.3390/healthcare11050681
dc.identifier.urihttps://hdl.handle.net/11616/101211
dc.identifier.volume11en_US
dc.identifier.wosWOS:000947298900001en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherMdpien_US
dc.relation.ispartofHealthcareen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectathleticsen_US
dc.subjectsprinten_US
dc.subjectpower athletesen_US
dc.subjectendurance athletesen_US
dc.subjectVDRen_US
dc.subjectrs2228570 polymorphismen_US
dc.titleEvaluation of the Association of VDR rs2228570 Polymorphism with Elite Track and Field Athletes' Competitive Performanceen_US
dc.typeArticleen_US

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