The ocular surface in the Behcet's disease patient

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dc.authoridGündüz, Abuzer/0000-0003-1752-6810
dc.authoridAKPOLAT, Nusret/0000-0002-9138-2117
dc.authorwosidGündüz, Abuzer/HLH-2417-2023
dc.authorwosidAKPOLAT, Nusret/ABF-6986-2020
dc.contributor.authorGunduz, Abuzer
dc.contributor.authorCumurcu, Tongabay
dc.contributor.authorDemirel, Ersin Ersan
dc.contributor.authorAkpolat, Nusret
dc.contributor.authorKarincaoglu, Yelda
dc.date.accessioned2024-08-04T20:36:13Z
dc.date.available2024-08-04T20:36:13Z
dc.date.issued2012
dc.departmentİnönü Üniversitesien_US
dc.description.abstractObjective: Evaluation of the morphological changes in conjunctival surface epithelial cells with impression cytology in Behget's disease patients. Patients: A total 01 89 eyes of 89 subjects were included. These consisted of 56 patients with inactive Behget's disease (group 1) and a control group of 33 age- and sex-matched subjects (group 2). Methods: Schirmer-I and break-up time (BUT) tests were used to evaluate the tear film of the subjects. Impression cytology was used to evaluate morphological changes of the conjunctival surface epithelial cells. The results of the 2 groups were compared. Results: The mean Schirmer-I test result was 8.59 +/- 4.83 in group 1 and 14.52 +/- 6.38 in group 2. There was a statistically significant difference between the 2 groups for this test (p = 0.001). The mean BUT test value was 10.05 +/- 3.26 in group 1 and 13.64 +/- 4.28 in group 2. There was a statistically significant difference between the 2 groups for this test (p = 0.001). The mean impression cytology score was 1.65 +/- 0.90 in group 1 and 1.39 +/- 0.96 in group 2. There was no statistically significant difference between the 2 groups when the cytology grade score was compared (p = 0.227). We found no statistically significant difference for age, gender, disease duration, systemic drug use, Schirmer-I, BUT, and impression cytology degrees between the Behget's disease patients with and without ocular involvement (p > 0.05). Conclusions: We found that there was a statistically significant difference between Behget's disease patients and normal subjects regarding the ocular film layer, but no difference regarding conjunctival surface epithelial morphology.en_US
dc.identifier.doi10.1016/j.jcjo.2012.04.014
dc.identifier.endpage434en_US
dc.identifier.issn0008-4182
dc.identifier.issn1715-3360
dc.identifier.issue5en_US
dc.identifier.pmid23036544en_US
dc.identifier.scopus2-s2.0-84869222926en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage429en_US
dc.identifier.urihttps://doi.org/10.1016/j.jcjo.2012.04.014
dc.identifier.urihttps://hdl.handle.net/11616/95857
dc.identifier.volume47en_US
dc.identifier.wosWOS:000310417100009en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherCanadian Ophthal Socen_US
dc.relation.ispartofCanadian Journal of Ophthalmology-Journal Canadien D Ophtalmologieen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectConjunctival Impression Cytologyen_US
dc.titleThe ocular surface in the Behcet's disease patienten_US
dc.typeArticleen_US

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