Activities of the hypothalamo-pituitary-adrenal axis and autonomic nervous system following a strong earthquake

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dc.authoridYilmaz, Yucehan/0000-0001-8422-0569
dc.authoriducar, cihat/0000-0003-3278-7779
dc.authoridYildiz, Sedat/0000-0002-7872-790X
dc.authorwosidYilmaz, Yucehan/JDD-8056-2023
dc.contributor.authorYilmaz, Yucehan
dc.contributor.authorUcar, Cihat
dc.contributor.authorYildiz, Sedat
dc.date.accessioned2024-08-04T20:54:27Z
dc.date.available2024-08-04T20:54:27Z
dc.date.issued2024
dc.departmentİnönü Üniversitesien_US
dc.description.abstractThis study aimed to investigate the effects of post-traumatic stress, caused by a strong earthquake, on the hypothalamo-pituitary-adrenal axis (HPA) and autonomous nervous system activity (ANS). Activities of the HPA (as salivary cortisol) and ANS (as heart-rate variability [HRV]) were measured following the 2020 Elazig (Turkiye) earthquake (6.8 Richter Scale, classified as strong). A total of 227 participants (103 men (45%) and 124 women (%55)) provided saliva samples twice, namely, 1 week and 6 weeks after the earthquake. Of these participants, HRV was measured in 51 participants by 5 min continuous electrocardiogram (ECG) recording. Frequency- and time-domain parameters of the HRV were calculated to assess the activity of ANS and low/high frequency (LF/HF) ratio was used as surrogate for sympathovagal balance. Salivary cortisol levels decreased from week 1 towards week 6 (17.40. 1.48 and 15.32. 1.37 ng/mL, respectively, p < 0.05). There were no gender differences (17.99. 2.63 and 16.90. 1.60 ng/mL, respectively for females and males, p > 0.05) for salivary cortisol levels. There were no differences in time- and frequency domain parameters of the HRV including LF/HF ratio (2.95 +/- 0.38 ms(2) and 3.60 +/- 0.70 ms(2), respectively for week 1 and 6, p > 0.05). The data show that HPA axis activity, but not that of the ANS, remains higher 1 week after the earthquake but decreases afterwards towards the sixth week, suggesting that the HPA axis might be responsible for the long-term effects of a traumatic event like a strong earthquake.en_US
dc.description.sponsorshipTUBITAK [106 O 010]en_US
dc.description.sponsorshipACKNOWLEDGEMENTS This study was partly supported by TUBITAK (#106 O 010).en_US
dc.identifier.doi10.1002/smi.3281
dc.identifier.issn1532-3005
dc.identifier.issn1532-2998
dc.identifier.issue1en_US
dc.identifier.pmid37291076en_US
dc.identifier.scopus2-s2.0-85161628327en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.urihttps://doi.org/10.1002/smi.3281
dc.identifier.urihttps://hdl.handle.net/11616/101399
dc.identifier.volume40en_US
dc.identifier.wosWOS:001005180800001en_US
dc.identifier.wosqualityQ1en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherWileyen_US
dc.relation.ispartofStress and Healthen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectautonomous nervous systemen_US
dc.subjectearthquakeen_US
dc.subjectHRVen_US
dc.subjecthypothalamo-pituitary-adrenal axisen_US
dc.subjectsalivary cortisolen_US
dc.titleActivities of the hypothalamo-pituitary-adrenal axis and autonomic nervous system following a strong earthquakeen_US
dc.typeArticleen_US

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