Increased thrombolysis in myocardial infarction frame counts in patients with isolated coronary artery ectasia

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dc.authorwosidIleri, Mehmet/A-6525-2018
dc.authorwosidÖZDEMIR, RENK/I-9560-2013
dc.contributor.authorSenen, K
dc.contributor.authorYetkin, E
dc.contributor.authorTurhan, H
dc.contributor.authorAtak, R
dc.contributor.authorSivri, N
dc.contributor.authorBattaloglu, B
dc.contributor.authorTandogan, I
dc.date.accessioned2024-08-04T20:56:13Z
dc.date.available2024-08-04T20:56:13Z
dc.date.issued2004
dc.departmentİnönü Üniversitesien_US
dc.description.abstractThe Thrombolysis in myocardial infarction (TIMI) frame count is a simple clinical tool for assessing quantitative indexes of coronary blood flow. This measurement has been significantly correlated with flow velocity measured with a flow-wire by several investigators during baseline conditions or hyperemia. In this study we aimed to evaluate the coronary flow in patients with isolated coronary artery ectasia by means of the TIMI frame count and to compare the results with those of patients with angiographically normal coronary arteries. The study population consisted of 37 patients with coronary artery ectasia only in the right coronary artery (RCA). The control group consisted of 31 patients with angiographically proven normal coronary arteries. Coronary artery ectasia was defined as nonobstructive lesions of the coronary arteries with a luminal dilatation 1.5-fold or more of the adjacent normal coronary segments. The TIMI frame count was determined for each major coronary artery in each patient according to the methods first described by Gibson et al. The TIMI frame count of RCA in the study group was significantly higher than in that of the control group (51+/-17 vs 25+/-8, P<0.0001). The TIMI frame counts of the study group for the left anterior descending and left circumflex coronary artery were also significantly higher than those of the control group (corrected TIMI frame count for LAD=42+/-11 vs 24+/-7, P<0.001; TIMI frame count for LCx=44+/-15 vs 25+/-9, P<0.001). In patients with coronary artery ectasia, the TIMI frame count of the RCA was higher than that of the left anterior descending and left circumflex coronary artery (51+/-17 vs 42+/-11 and 44+/-15, respectively, P<0.05). We have shown increased TIMI frame counts in patients with isolated coronary artery ectasia and suggest that the pathophysiological mechanism of coronary artery ectasia is not a focal disease. TIMI frame counts can be regarded as an index of the severity of impaired coronary flow in patients with coronary artery ectasia.en_US
dc.identifier.doi10.1007/s00380-003-0722-z
dc.identifier.endpage26en_US
dc.identifier.issn0910-8327
dc.identifier.issn1615-2573
dc.identifier.issue1en_US
dc.identifier.pmid14685751en_US
dc.identifier.scopus2-s2.0-9144228675en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage23en_US
dc.identifier.urihttps://doi.org/10.1007/s00380-003-0722-z
dc.identifier.urihttps://hdl.handle.net/11616/102139
dc.identifier.volume19en_US
dc.identifier.wosWOS:000187504300005en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherSpringeren_US
dc.relation.ispartofHeart and Vesselsen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectcoronary artery ectasiaen_US
dc.subjectthrombolysis in myocardial infarction frame counten_US
dc.subjectcoronary flowen_US
dc.titleIncreased thrombolysis in myocardial infarction frame counts in patients with isolated coronary artery ectasiaen_US
dc.typeArticleen_US

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