Evaluation of pleth variability index as a predictor of fluid responsiveness during orthotopic liver transplantation

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dc.authoridDurmus, Mahmut/0000-0001-9594-9064
dc.authoridYologlu, Saim/0000-0002-9619-3462
dc.authoridToprak, Hüseyin İlksen/0000-0001-9293-8116
dc.authoridaydogan, mustafa said/0000-0002-7106-1156
dc.authoridErdogan Kayhan, Gulay/0000-0002-2635-9295
dc.authorwosidDurmus, Mahmut/ABH-3006-2020
dc.authorwosidYologlu, Saim/ABI-8014-2020
dc.authorwosidDurmuş, Mahmut/AAG-3377-2019
dc.authorwosidToprak, Hüseyin İlksen/AAN-4023-2020
dc.authorwosidaydogan, mustafa said/AAA-2828-2021
dc.authorwosidErdogan Kayhan, Gulay/JVZ-0037-2024
dc.contributor.authorKonur, Huseyin
dc.contributor.authorKayhan, Gulay Erdogan
dc.contributor.authorToprak, Huseyin Ilksen
dc.contributor.authorBucak, Nizamettin
dc.contributor.authorAydogan, Mustafa Said
dc.contributor.authorYologlu, Saim
dc.contributor.authorDurmus, Mahmut
dc.date.accessioned2024-08-04T20:42:31Z
dc.date.available2024-08-04T20:42:31Z
dc.date.issued2016
dc.departmentİnönü Üniversitesien_US
dc.description.abstractFluid management is challenging and still remains controversial in orthotopic liver transplantation (OLT). The pleth variability index (PVI) has been shown to be a reliable predictor of fluid responsiveness of perioperative and critically ill patients; however, it has not been evaluated in OLT. This study was designed to examine whether the PVI can reliably predict fluid responsiveness in OLT and to compare PVI with other hemodynamic indexes that are measured using the PiCCO(2) monitoring system. Twenty-five patients were enrolled in this study. Each patient was monitored using the noninvasive Masimo and PiCCO(2) monitoring system. PVI was obtained with a Masimo pulse oximeter. Cardiac index was obtained using a transpulmonary thermodilution technique (CITPTD). Stroke volume variation (SVV), pulse pressure variation, and systemic vascular resistance index were measured using the PiCCO(2) system. Fluid loading (10 mL/kg colloid) was performed at two different phases during the operation, and fluid responsiveness was defined as an increase in CITPTD >= 15%. During the dissection phase and the anhepatic phase, respectively, 14 patients (56%) and 18 patients (75%) were classified as responders. There were no differences between the baseline values of the PVI of responders and nonresponders. Area under the curve for PVI was 0.56 (sensitivity 35%, specificity 90%, p = 0.58) at dissection phase, and was 0.55 (sensitivity 55%, specificity 66%, p = 0.58) at anhepatic phase. Of the parameters, a higher area under the curve value was found for SVV. We conclude that PVI was unable to predict fluid responsiveness with sufficient accuracy in patients undergoing OLT, but the SVV parameter was reliable. Copyright (C) 2016, Kaohsiung Medical University. Published by Elsevier Taiwan LLC.en_US
dc.description.sponsorshipInonu University Department of Scientific Research Projects [2012/58]en_US
dc.description.sponsorshipThis study was supported by the Inonu University Department of Scientific Research Projects (Project number: 2012/58).en_US
dc.identifier.doi10.1016/j.kjms.2016.05.014
dc.identifier.endpage380en_US
dc.identifier.issn1607-551X
dc.identifier.issn2410-8650
dc.identifier.issue7en_US
dc.identifier.pmid27450027en_US
dc.identifier.scopus2-s2.0-84977470376en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage373en_US
dc.identifier.urihttps://doi.org/10.1016/j.kjms.2016.05.014
dc.identifier.urihttps://hdl.handle.net/11616/97397
dc.identifier.volume32en_US
dc.identifier.wosWOS:000380757500006en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherWileyen_US
dc.relation.ispartofKaohsiung Journal of Medical Sciencesen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectFluid responsivenessen_US
dc.subjectLiver transplantationen_US
dc.subjectPleth variability indexen_US
dc.titleEvaluation of pleth variability index as a predictor of fluid responsiveness during orthotopic liver transplantationen_US
dc.typeArticleen_US

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