Histopathological Evaluation of Gallbladder Specimens Obtained From Living Liver Donors

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dc.authoridGÜRLÜLER, ERCÜMENT/0000-0002-6008-5494
dc.authoridSARICI, KEMAL BARIŞ/0000-0001-9595-1906
dc.authoridÇOLAK, CEMİL/0000-0001-5406-098X
dc.authoridAkbulut, Sami/0000-0002-6864-7711
dc.authoridciftci, felat/0000-0002-8958-7121
dc.authorwosidGÜRLÜLER, ERCÜMENT/X-7425-2018
dc.authorwosidSARICI, KEMAL BARIŞ/ABI-4356-2020
dc.authorwosidÇOLAK, CEMİL/ABI-3261-2020
dc.authorwosidAkbulut, Sami/L-9568-2014
dc.contributor.authorAkbulut, Sami
dc.contributor.authorSarici, Kemal Baris
dc.contributor.authorToprak, Serhat
dc.contributor.authorTuncer, Adem
dc.contributor.authorCiftci, Felat
dc.contributor.authorKaradag, Nese
dc.contributor.authorGurluler, Ercument
dc.date.accessioned2024-08-04T20:53:21Z
dc.date.available2024-08-04T20:53:21Z
dc.date.issued2023
dc.departmentİnönü Üniversitesien_US
dc.description.abstractBackground. Cholecystectomy is routinely performed during living donor hepatectomy both to see the structure of the biliary tract and to determine the demarcation line based on the biliary tract junction. This study aims to present the general histopathological features of the gallbladder specimen obtained from living liver donors (LLD). Methods. Data from 2577 LLDs who underwent living donor hepatectomy (n = 2511) or aborted living donor hepatectomy (n = 66) in our Liver Transplantation Institute between September 2005 and June 2021 were analyzed retrospectively. Age, gender, macroscopic (length, diameter, and wall thickness), and microscopic (histopathological) features of the gallbladder of the LLDs were recorded for use in this study. Results. A total of 2493 LLDs (men: 1486, women: 1007) with a median age of 29 years (interquartile range [IQR]: 13) met the inclusion criteria in this study. The median length, width and wall thickness of the gallbladder specimens were measured as 70 mm (IQR: 20), 50 mm (IQR: 20), and 2 mm (IQR: 1), respectively. The most common histopathological findings are normal structure (2026; 81.3%), chronic cholecystitis (n = 446; 17.9%), adenomyomatosis (n = 9), and papillary hyperplasia (n = 6), respectively. The most common pathologic findings in the gallbladder lumen are cholesterolosis (n = 207; 0.4%), cholelithiasis (n = 53), cholesterol polyp (n = 31), and noncholesterol polyp (n = 19), respectively. Significant differences were detected between the male and (content) (P < .001), and lymph node around the gallbladder (P = .015). Conclusions. The results we obtained in this study are true gallbladder pathologies that can be detected in healthy people. In this study, it was shown that the diameter and size of the gallbladder were larger in men, whereas the incidence of cholesterolosis and cholelithiasis was higher in women.en_US
dc.identifier.doi10.1016/j.transproceed.2022.11.010
dc.identifier.endpage1272en_US
dc.identifier.issn0041-1345
dc.identifier.issn1873-2623
dc.identifier.issue5en_US
dc.identifier.pmid36604250en_US
dc.identifier.scopus2-s2.0-85145701833en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage1267en_US
dc.identifier.urihttps://doi.org/10.1016/j.transproceed.2022.11.010
dc.identifier.urihttps://hdl.handle.net/11616/101098
dc.identifier.volume55en_US
dc.identifier.wosWOS:001035770300001en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherElsevier Science Incen_US
dc.relation.ispartofTransplantation Proceedingsen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectCholecystectomy Specimensen_US
dc.subjectTransplantationen_US
dc.subjectHepatectomyen_US
dc.subjectPreservationen_US
dc.subjectMetaplasiaen_US
dc.subjectFeaturesen_US
dc.titleHistopathological Evaluation of Gallbladder Specimens Obtained From Living Liver Donorsen_US
dc.typeArticleen_US

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