Does Rocuroinum Dose Adjusted Due to Lean Body Weight Provide Adequate Intubation Conditions?: A Prospective Observational Study

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dc.authoridcolak, yusuf ziya/0000-0002-8729-8705
dc.authoridDurmus, Mahmut/0000-0001-9594-9064
dc.authoriderdogan, mehmet ali/0000-0002-1713-5695
dc.authoriddemiroz, duygu/0000-0002-4241-4514
dc.authoridALTUNKAYA, NESLIHAN/0000-0002-1004-4889
dc.authorwosidcolak, yusuf ziya/ABH-3032-2020
dc.authorwosidDurmus, Mahmut/ABH-3006-2020
dc.authorwosiderdogan, mehmet ali/ABI-4675-2020
dc.authorwosiddemiroz, duygu/ABI-8041-2020
dc.contributor.authorDemiroz, Duygu
dc.contributor.authorColak, Yusuf Ziya
dc.contributor.authorIclek, Sumeyye Koc
dc.contributor.authorErdogan, Mehmet Ali
dc.contributor.authorYagci, Neslihan Altunkaya
dc.contributor.authorDurmus, Mahmut
dc.contributor.authorGulhas, Nurcin
dc.date.accessioned2024-08-04T20:53:04Z
dc.date.available2024-08-04T20:53:04Z
dc.date.issued2022
dc.departmentİnönü Üniversitesien_US
dc.description.abstractIntroduction and Aim. There is no consensus on the weight parameters to use when titrating the dosage of the neuromuscular blocking agents during intubation. In our study, we administered rocuronium, based on either the lean body weight (LBW) or the total body weight in patients with body mass index (BMI) of 18.5 to 34.9 and compared the duration of action of the drug and its effects on tracheal intubation conditions and hemodynamic parameters. Methods. This is a prospective, observational study. Patients between the ages of 18 and 65 with BMI of 18.5-34.9, who are expected to be under general anesthesia for less than 6 hours, were divided into 3 groups according to their BMI (Group 1 BMI = 18.5-24.9, Group 2 BMI = 25-29.9, Group 3 BMI = 30-34.9). These groups were randomly divided into 2 subgroups: Groups LBW; 1 LBW, 2 LBW, and 3 LBW were given rocuronium intubation dosages based on their LBW while control groups; 1K, 2K, and 3K were given 0.6 mg/kg rocuronium according to their total body weight. The data on the duration of action of rocuronium and its effects on the endotracheal intubation conditions were evaluated. Results. In Group 1, T1 time was found to be significantly longer (p=0.001). Intubation score and the use of additional rocuronium dose were found to be significantly higher in Group 1 LBW than in Group 1K (p=0.001). In Group 1, an additional rocuronium dose was needed to achieve optimal intubation conditions for subgroup 1 LBW. Rocuronium duration of action was found to be significantly longer in control groups 2 and 3, that received TBW-based dosage. Conclusion. In adult patients with a BMI of 18.5 and 24.9 BMI, we report optimal intubation conditions with the LBW-adjusted rocuronium dosage.en_US
dc.identifier.doi10.1155/2022/6840960
dc.identifier.issn1368-5031
dc.identifier.issn1742-1241
dc.identifier.pmid36263238en_US
dc.identifier.scopus2-s2.0-85139994097en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.urihttps://doi.org/10.1155/2022/6840960
dc.identifier.urihttps://hdl.handle.net/11616/100945
dc.identifier.volume2022en_US
dc.identifier.wosWOS:000870004000001en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherWiley-Hindawien_US
dc.relation.ispartofInternational Journal of Clinical Practiceen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectRocuroniumen_US
dc.subjectInductionen_US
dc.subjectDurationen_US
dc.titleDoes Rocuroinum Dose Adjusted Due to Lean Body Weight Provide Adequate Intubation Conditions?: A Prospective Observational Studyen_US
dc.typeArticleen_US

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