Oxidant/antioxidant parameters and their relationship with chemotherapy in Hodgkin's lymphoma

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dc.authoridErkurt, Mehmet Ali/0000-0002-3285-417X
dc.authoridKAYA, Emin/0000-0001-8605-8497
dc.authorwosidErkurt, Mehmet Ali/ABI-7232-2020
dc.authorwosidKAYA, Emin/W-2951-2017
dc.contributor.authorKaya, E
dc.contributor.authorKeskin, L
dc.contributor.authorAydogdu, I
dc.contributor.authorKuku, I
dc.contributor.authorBayraktar, N
dc.contributor.authorErkut, MA
dc.date.accessioned2024-08-04T20:15:11Z
dc.date.available2024-08-04T20:15:11Z
dc.date.issued2005
dc.departmentİnönü Üniversitesien_US
dc.description.abstractThis study investigated changing levels of serum oxidant/antioxidant with chemotherapy and their relation to treatment in 34 Hodgkin's lymphoma patients. The patient population consisted of 19 males and 15 females. Mean age was 30.41 12.08 years. All patients received the adriamycin, bleomycin, vincristine and dexamethasone (ABVD) treatment protocol. Blood samples were taken before treatment, and on days 1 and 7 during treatment for measurement of superoxide dismutase (SOD), glutathione peroxidase (GSH-Px), catalase (CAT), malondialdehyde (MDA), nitric oxide (NO) and enzyme activities. After ABVD treatment, mean free radical levels were increased and antioxidant levels were significantly decreased in the serum. ABVD treatment results in an increase of free radical levels and a decrease of antioxidant levels in the serum of patients with Hodgkin's lymphoma.en_US
dc.identifier.doi10.1177/147323000503300611
dc.identifier.endpage692en_US
dc.identifier.issn0300-0605
dc.identifier.issn1473-2300
dc.identifier.issue6en_US
dc.identifier.pmid16372587en_US
dc.identifier.scopus2-s2.0-29444458058en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage687en_US
dc.identifier.urihttps://doi.org/10.1177/147323000503300611
dc.identifier.urihttps://hdl.handle.net/11616/94205
dc.identifier.volume33en_US
dc.identifier.wosWOS:000233888700011en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherSage Publications Ltden_US
dc.relation.ispartofJournal of International Medical Researchen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectABVDen_US
dc.subjectcisplatinen_US
dc.subjectcancer chemotherapyen_US
dc.subjectoxidanten_US
dc.subjectantioxidant free radicalsen_US
dc.subjectHodgkin's lymphomaen_US
dc.subjectspectrophotometryen_US
dc.subjectspectrofluorometryen_US
dc.titleOxidant/antioxidant parameters and their relationship with chemotherapy in Hodgkin's lymphomaen_US
dc.typeArticleen_US

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