Occult hepatitis B infection in Turkish HIV-infected patients: A multicentre, retrospective, cross-sectional study, Schindler study

Basit Öğe Kaydı
dc.authoridmete, ayşe özlem/0000-0003-0994-4465
dc.authoridtoplu, sibel altunışık/0000-0002-2915-4666
dc.authoridÖren, Meryem Merve/0000-0002-3383-7830
dc.authoridÜNLÜ, GÜLTEN/0000-0002-1260-5109
dc.authoridKalkan, İrem Akdemir/0000-0001-5136-9148
dc.authoridBAYINDIR, Yasar/0000-0003-3930-774X
dc.authoridkomur, suheyla/0000-0003-2414-559X
dc.authorwosidmete, ayşe özlem/AAA-5072-2021
dc.authorwosidKarasahin, Omer/JBJ-0597-2023
dc.authorwosidtoplu, sibel altunışık/ABH-5816-2020
dc.authorwosidÖren, Meryem Merve/AAD-1806-2020
dc.authorwosidTaşova, Yeşim/JVY-8831-2024
dc.authorwosidyıldız, yeşim/AAD-2219-2022
dc.authorwosidKaraoğlan, İlkay/AAG-9240-2020
dc.contributor.authorUnlu, Gulten
dc.contributor.authorYildiz, Yesim
dc.contributor.authorOren, Meryem Merve
dc.contributor.authorCabalak, Mehmet
dc.contributor.authorMete, Ozlem
dc.contributor.authorKomur, Suheyla
dc.contributor.authorYildirim, Figen
dc.date.accessioned2024-08-04T20:50:16Z
dc.date.available2024-08-04T20:50:16Z
dc.date.issued2021
dc.departmentİnönü Üniversitesien_US
dc.description.abstractObjective Occult hepatitis B infection (OHBI) appears to have a higher prevalence in populations at high risk for hepatitis B virus (HBV) infection with concomitant liver disease. The aim was to assess the prevalence of OHBI in a sample of human immunodeficiency virus -1 positive and HBV surface antigen-negative (HIV-1+/HBsAg-) Turkish patients. Methods Ten centres in Turkey were included in the study. Patients were selected on the basis of a power calculation with a known population size of HIV-positive patients and a reported prevalence of OHBI. Gender, age, occupation, place of residence, treatment and clinical status, and laboratory results, including immunodeficiency panel, antibody tests, hemogram, biochemistry, and coagulation studies were evaluated retrospectively. Results The number of HIV-infected patients followed in these centres was 3172 and the sample population numbered 278. All 278 were HBsAg negative. The mean age of the sample was 37.2 +/- 13.1 years and 235 (84.5%) were male. All but one patient (99.6%) had been treated with antiretroviral therapy. Of the 278 patients, 169 (60.6%) were positive for Anti-HBs and 125 (44.8%) were positive for Anti-HBc IgG. HIV RNA was detected in 203/278 (73%) of the patients. Four HBV DNA (1.4%) were diagnosed with OHBI. There was no significant difference in hemogram, hemoglobin or bilirubin concentrations in those with OHBI compared with the other patients. Conclusion In a representative sample of HIV+ patients from 10 Turkish centres, the prevalence of OHBI was found to be 1.4%. In HIV positive patients, it is important to identify those with OHBI for optimal clinical management and prognosis.en_US
dc.identifier.doi10.1111/ijcp.14358
dc.identifier.issn1368-5031
dc.identifier.issn1742-1241
dc.identifier.issue9en_US
dc.identifier.pmid33977603en_US
dc.identifier.scopus2-s2.0-85106620811en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.urihttps://doi.org/10.1111/ijcp.14358
dc.identifier.urihttps://hdl.handle.net/11616/99956
dc.identifier.volume75en_US
dc.identifier.wosWOS:000654928300001en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherWiley-Hindawien_US
dc.relation.ispartofInternational Journal of Clinical Practiceen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectVirus Coinfectionen_US
dc.subjectPrevalenceen_US
dc.subjectHbven_US
dc.titleOccult hepatitis B infection in Turkish HIV-infected patients: A multicentre, retrospective, cross-sectional study, Schindler studyen_US
dc.typeArticleen_US

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayın Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu