Does atopy affect the course of viral pneumonia?

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dc.contributor.authorCatal, F
dc.contributor.authorGirit, S
dc.contributor.authorCan, D
dc.contributor.authorErdem, S. B
dc.contributor.authorSen, V
dc.date.accessioned2019-07-10T10:16:15Z
dc.date.available2019-07-10T10:16:15Z
dc.date.issued2018
dc.departmentİnönü Üniversitesien_US
dc.description.abstractBackground: The presence of atopy is considered as a risk factor for severe respiratory symptoms in children. The objective of this study was to examine the effect of atopy on the course of disease in children hospitalised with viral pneumonia. Methods: Children between the ages of 1 and 6 years hospitalised due to viral pneumonia between the years of 2013 and 2016 were included to this multicentre study. Patients were classified into two groups as mild-moderate and severe according to the course of pneumonia. Presence of atopy was evaluated with skin prick tests. Groups were compared to evaluate the risk factors associated with severe viral pneumonia. Results: A total of 280 patients from nine centres were included in the study. Of these patients, 163 (58.2%) were male. Respiratory syncytial virus (29.7%), Influenza A (20.5%), rhinovirus (18.9%), adenovirus (10%), human metapneumovirus (8%), parainfluenza (5.2%), coronavirus (6%), and bocavirus (1.6%) were isolated from respiratory samples. Eighty-five (30.4%) children had severe pneumonia. Atopic sensitisation was found in 21.4% of the patients. Ever wheezing (RR: 1.6, 95% CI: 1.1-2.4), parental asthma (RR: 1.5, 95% CI: 1.1-2.2), other allergic diseases in the family (RR: 1.8, 95% CI: 1.2-2.9) and environmental tobacco smoke (RR: 1.6, 95% CI: 1.1-3.5) were more common in the severe pneumonia group. Conclusions: When patients with mild-moderate pneumonia were compared to patients with severe pneumonia, frequency of atopy was not different between the two groups. However, parental asthma, ever wheezing and environmental tobacco smoke exposure are risk factors for severe viral pneumonia in children. (C) 2017 SEICAP. Published by Elsevier Espana, S.L.U. All rights reserved.en_US
dc.identifier.citationCatal, F. Girit, S. Can, D. Erdem, S. B. Sen, V. (2018). Does atopy affect the course of viral pneumonia?Cilt:46. Sayı:2. 119-126 ss.en_US
dc.identifier.doi10.1016/j.aller.2017.04.003en_US
dc.identifier.endpage126en_US
dc.identifier.issue2en_US
dc.identifier.startpage119en_US
dc.identifier.urihttps://hdl.handle.net/11616/12483
dc.identifier.volume46en_US
dc.language.isoenen_US
dc.publisherElsevıer espana slu, av josep tarradellas, 20-30, 1era planta, barcelona, cp-08029, spaınen_US
dc.relation.ispartofAllergologıa et ımmunopathologıaen_US
dc.rightsinfo:eu-repo/semantics/restrictedAccessen_US
dc.subjectRısk-factorsen_US
dc.subjectpneumococcal dıseaseen_US
dc.subjectvırus/allergen ınteractıonsen_US
dc.subjectaırway epıthelıumen_US
dc.subjectchıldren youngeren_US
dc.subjectasthmaen_US
dc.subjectınfectıonsen_US
dc.subjectıdentıfıcatıonen_US
dc.subjectexacerbatıonsen_US
dc.subjectexposureen_US
dc.titleDoes atopy affect the course of viral pneumonia?en_US
dc.typeArticleen_US

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