Association Between Initial Findings Leading to Behcet's Disease Diagnosis and Further Organ Involvements

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dc.authoridCenk, Hülya/0000-0003-4871-6342
dc.authoridARSLAN, SELAMI/0000-0003-2500-633X
dc.authorwosidCenk, Hülya/A-1293-2016
dc.contributor.authorYanatma, Irem
dc.contributor.authorSarac, Gulbahar
dc.contributor.authorCenk, Hulya
dc.contributor.authorArslan, Selami
dc.contributor.authorDurmaz, Imge
dc.contributor.authorAy, Gonca
dc.date.accessioned2024-08-04T20:55:58Z
dc.date.available2024-08-04T20:55:58Z
dc.date.issued2022
dc.departmentİnönü Üniversitesien_US
dc.description.abstractObjectives: Studies show that the symptoms are clustered in certain ways in Behcet's disease (BD), which causes involvement of multiple organs. We aimed to investigate the association between clinical findings at onset and further organ involvements, which may occur during follow-up. Materials and Methods: A total of 363 patients diagnosed with BD in accordance with the International Criteria for BD (ICBD) between 2003 and 2019 at the Inonu University were included in the study, and all the first findings were compared with further organ involvements. Results: A statistical significance was detected between erythema nodosum like lesions and both pulmonary (P = 0.002) and vascular (P = 0.022) involvements. The frequency of neurological involvement was higher in patients with papulopustular/pseudo-follicular lesions (P = 0.043). Gastrointestinal involvement was detected in 33.3% of the patients with herpetiform aphthae. The frequency of ocular involvement was significantly higher in patients with a negative pathergy test result (P = 0.013). Conclusion: The clinical clusters in BD may provide a predictive value about the disease course for clinicians. Although it has been shown that there is an association between some clinical findings and involvements which are mentioned before, this is one of the most comprehensive studies according to us. The clinical clusters in BD may provide a predictive value about the disease course for clinicians. Although it has been shown that there is an association between some clinical findings and involvements in the literature, this is one of the most comprehensive studies as far as we know.en_US
dc.identifier.doi10.4103/tjd.tjd_24_22
dc.identifier.endpage97en_US
dc.identifier.issn1307-7635
dc.identifier.issn1308-5255
dc.identifier.issue3en_US
dc.identifier.scopus2-s2.0-85192262703en_US
dc.identifier.scopusqualityQ4en_US
dc.identifier.startpage92en_US
dc.identifier.urihttps://doi.org/10.4103/tjd.tjd_24_22
dc.identifier.urihttps://hdl.handle.net/11616/101970
dc.identifier.volume16en_US
dc.identifier.wosWOS:000859411900004en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherWolters Kluwer Medknow Publicationsen_US
dc.relation.ispartofTurk Dermatoloji Dergisi-Turkish Journal of Dermatologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectGastrointestinalen_US
dc.subjectneuro-Behceten_US
dc.subjectocularen_US
dc.subjectpulmonaryen_US
dc.subjectvascularen_US
dc.titleAssociation Between Initial Findings Leading to Behcet's Disease Diagnosis and Further Organ Involvementsen_US
dc.typeArticleen_US

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