Is deep brain stimulation useful in Lance-Adams syndrome?

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dc.authoridOZTURK OZLUK, Gulsah/0000-0002-2253-9037
dc.authoridSamanci, Yavuz/0000-0001-8952-6866
dc.authoridTASCI, IREM/0000-0001-7069-769X
dc.authoridPeker, Selcuk/0000-0003-3057-3355
dc.authorwosidOZTURK OZLUK, Gulsah/IZQ-4598-2023
dc.authorwosidSamanci, Yavuz/I-1408-2016
dc.authorwosidTASCI, IREM/AAW-3048-2020
dc.authorwosidPeker, Selcuk/D-2516-2015
dc.contributor.authorozturk, Gulsah
dc.contributor.authorTasci, Irem
dc.contributor.authorSamanci, Mustafa Yavuz
dc.contributor.authorPeker, Selcuk
dc.date.accessioned2024-08-04T20:59:46Z
dc.date.available2024-08-04T20:59:46Z
dc.date.issued2021
dc.departmentİnönü Üniversitesien_US
dc.description.abstractLance-Adams syndrome (LAS) is a chronic post-hypoxic myoclonus that occurs after successful cardiopulmonary resuscitation. Although many drugs are available to treat this condition, the underlying mechanism of the disease is yet to be understood. Deep brain stimulation (DBS) has been attempted and proven to be partially successful in treating LAS in several cases. Here, we present a 40-year-old woman who developed myoclonus subsequent to cardiopulmonary arrest (CPA) that occurred after her first cesarean delivery at the age of 26 years. The patient underwent implantation of bilateral globus pallidus interna (GPi)-DBS about 14 years after disease onset. Regarding Unified Myoclonus Rating Scale (UMRS), 8% and 20% improvements were observed in action and resting myoclonus, respectively, with high-frequency stimulation as a result of the 3-year follow-up study. In this case, neuromodulation therapy applied 14 years after hypoxia-causing LAS was not sufficiently beneficial.en_US
dc.identifier.doi10.54029/2021ykj
dc.identifier.endpage620en_US
dc.identifier.issn1823-6138
dc.identifier.issue3en_US
dc.identifier.startpage617en_US
dc.identifier.urihttps://doi.org/10.54029/2021ykj
dc.identifier.urihttps://hdl.handle.net/11616/103511
dc.identifier.volume26en_US
dc.identifier.wosWOS:000701285900026en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.language.isoenen_US
dc.publisherAsean Neurological Assocen_US
dc.relation.ispartofNeurology Asiaen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectDeep brain stimulationen_US
dc.subjectmyoclonusen_US
dc.subjectcardiopulmonary resuscitationen_US
dc.subjectpost-hypoxic myoclonusen_US
dc.titleIs deep brain stimulation useful in Lance-Adams syndrome?en_US
dc.typeArticleen_US

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