The Relationship Between Hepatic Activity Index and Serum Tumor Necrosis Factor Alpha Levels in Patients with Chronic Active Hepatitis-B and Chronic Active Hepatitis-C
dc.contributor.author | Bilgiç, Yılmaz | |
dc.contributor.author | Harputluoğlu, Muhsin Murat Muhip | |
dc.contributor.author | Dal, Mehmet Burak | |
dc.contributor.author | Bozan, Mehmet Buğra | |
dc.contributor.author | Şahin, Abdurrahman | |
dc.contributor.author | Yazar, Fatih Mehmet | |
dc.contributor.author | Çağın, Yasir Furkan | |
dc.date.accessioned | 2021-12-03T09:54:02Z | |
dc.date.available | 2021-12-03T09:54:02Z | |
dc.date.issued | 2015 | |
dc.department | İnönü Üniversitesi | en_US |
dc.description.abstract | Abstract: In the present study, we investigated the relationship between serum TNF-? levels and hepatic activity in liver biopsies of chronic hepatitis B and C patients.The study was performed on 30 chronic hepatitis B patients, 25 chronic hepatitis C patients and 25 healthy controls. Serum samples of patients who underwent biopsy and healthy controls were collected. Control group was seronegative for hepatitis and had normal liver function tests. TNF- ? levels measured by ELISA. Knodell’s hepatic activity index was used in evaluation of liver biopsies. Serum TNF? levels were determined higher in chronic hepatitis B and C patients than control group. HAI and TNF- ? compared in chronic hepatitis B and C patients. Although we detected a relationship between HAI and TNF-? levels in chronic hepatitis B patients, no true correlation was shown in chronic hepatitis C patients. Cytokines have an important role in progression of chronic hepatitis B and C infections. There is a relationship between hepatic activity index and TNF-? level in chronic hepatitis B infection.But There is not relationship between hepatic activity index and chronic hepatitis C infection.only in two patients and both of them where in the middle of their reproductive age while as symptomatic ovarian cysts was a more common finding in unmarried females in 21-28 years of age group. This study concluded that laparoscopy has a diagnostic as well as a therapeutic implication in management of NSAP | en_US |
dc.identifier.citation | BİLGİÇ Y,HARPUTLUOĞLU M. M. M,YAPRAK B,DAL M. B,BOZAN M. B,ŞAHİN A,YAZAR F. M,ÇAĞIN Y. F,OKÇU N (2015). The Relationship Between Hepatic Activity Index and Serum Tumor Necrosis Factor Alpha Levels in Patients with Chronic Active Hepatitis-B and Chronic Active Hepatitis-C. Medicine Science, 4(4), 2772 - 2781. | en_US |
dc.identifier.endpage | 2781 | en_US |
dc.identifier.issn | 2147-0634 | |
dc.identifier.issue | 4 | en_US |
dc.identifier.startpage | 2772 | en_US |
dc.identifier.trdizinid | 249488 | en_US |
dc.identifier.uri | https://hdl.handle.net/11616/43811 | |
dc.identifier.uri | https://search.trdizin.gov.tr/yayin/detay/249488 | |
dc.identifier.volume | 4 | en_US |
dc.indekslendigikaynak | TR-Dizin | en_US |
dc.language.iso | en | en_US |
dc.relation.ispartof | Medicine Science | en_US |
dc.relation.publicationcategory | Makale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
dc.rights | info:eu-repo/semantics/openAccess | en_US |
dc.title | The Relationship Between Hepatic Activity Index and Serum Tumor Necrosis Factor Alpha Levels in Patients with Chronic Active Hepatitis-B and Chronic Active Hepatitis-C | en_US |
dc.type | Article | en_US |