The Relationship Between Hepatic Activity Index and Serum Tumor Necrosis Factor Alpha Levels in Patients with Chronic Active Hepatitis-B and Chronic Active Hepatitis-C

dc.contributor.authorBilgiç, Yılmaz
dc.contributor.authorHarputluoğlu, Muhsin Murat Muhip
dc.contributor.authorDal, Mehmet Burak
dc.contributor.authorBozan, Mehmet Buğra
dc.contributor.authorŞahin, Abdurrahman
dc.contributor.authorYazar, Fatih Mehmet
dc.contributor.authorÇağın, Yasir Furkan
dc.date.accessioned2021-12-03T09:54:02Z
dc.date.available2021-12-03T09:54:02Z
dc.date.issued2015
dc.departmentİnönü Üniversitesien_US
dc.description.abstractAbstract: In the present study, we investigated the relationship between serum TNF-? levels and hepatic activity in liver biopsies of chronic hepatitis B and C patients.The study was performed on 30 chronic hepatitis B patients, 25 chronic hepatitis C patients and 25 healthy controls. Serum samples of patients who underwent biopsy and healthy controls were collected. Control group was seronegative for hepatitis and had normal liver function tests. TNF- ? levels measured by ELISA. Knodell’s hepatic activity index was used in evaluation of liver biopsies. Serum TNF? levels were determined higher in chronic hepatitis B and C patients than control group. HAI and TNF- ? compared in chronic hepatitis B and C patients. Although we detected a relationship between HAI and TNF-? levels in chronic hepatitis B patients, no true correlation was shown in chronic hepatitis C patients. Cytokines have an important role in progression of chronic hepatitis B and C infections. There is a relationship between hepatic activity index and TNF-? level in chronic hepatitis B infection.But There is not relationship between hepatic activity index and chronic hepatitis C infection.only in two patients and both of them where in the middle of their reproductive age while as symptomatic ovarian cysts was a more common finding in unmarried females in 21-28 years of age group. This study concluded that laparoscopy has a diagnostic as well as a therapeutic implication in management of NSAPen_US
dc.identifier.citationBİLGİÇ Y,HARPUTLUOĞLU M. M. M,YAPRAK B,DAL M. B,BOZAN M. B,ŞAHİN A,YAZAR F. M,ÇAĞIN Y. F,OKÇU N (2015). The Relationship Between Hepatic Activity Index and Serum Tumor Necrosis Factor Alpha Levels in Patients with Chronic Active Hepatitis-B and Chronic Active Hepatitis-C. Medicine Science, 4(4), 2772 - 2781.en_US
dc.identifier.endpage2781en_US
dc.identifier.issn2147-0634
dc.identifier.issue4en_US
dc.identifier.startpage2772en_US
dc.identifier.trdizinid249488en_US
dc.identifier.urihttps://hdl.handle.net/11616/43811
dc.identifier.urihttps://search.trdizin.gov.tr/yayin/detay/249488
dc.identifier.volume4en_US
dc.indekslendigikaynakTR-Dizinen_US
dc.language.isoenen_US
dc.relation.ispartofMedicine Scienceen_US
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.titleThe Relationship Between Hepatic Activity Index and Serum Tumor Necrosis Factor Alpha Levels in Patients with Chronic Active Hepatitis-B and Chronic Active Hepatitis-Cen_US
dc.typeArticleen_US

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