Treatment of Pneumocystis jirovecii Pneumonia with Caspofungin and Clindamycin: An HIV Patient and Literature Review

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dc.authoridInkaya, Ahmet Cagkan/0000-0001-7943-8715
dc.contributor.authorYilmaz, Gul Ruhsar
dc.contributor.authorKaya, Onur
dc.contributor.authorInkaya, Ahmet Cagkan
dc.contributor.authorUnal, Onur
dc.contributor.authorTemel, Esra Nurlu
dc.contributor.authorAkcam, Fusun Zeynep
dc.contributor.authorCetin, Emel Sesli
dc.date.accessioned2024-08-04T20:11:43Z
dc.date.available2024-08-04T20:11:43Z
dc.date.issued2023
dc.departmentİnönü Üniversitesien_US
dc.description.abstractThe first-line treatment for Pneumocystis jirovecii pneumonia (PCP) is trimethoprim-sulfamethoxazole (TMP-SMZ). However, some cases require alternative agents due to the side effects of TMP-SMZ. Treatment with TMP-SMZ was initiated in an HIV-positive patient with microbiologically confirmed PCP, who presented with acute renal failure on admission. On the third day of treatment, TMP-SMZ was discontinued due to worsening renal function. Subsequently, clindamycin was initiated in combination with caspofungin. Although caspofungin-based therapies were shown to be effective against Pneumocystis in animal models, clinical experience in humans is limited. The patient was treated successfully with clindamycin combined with caspofungin.en_US
dc.identifier.doi10.5578/flora.202401981
dc.identifier.endpage144en_US
dc.identifier.issn1300-932X
dc.identifier.issn2602-2842
dc.identifier.issue1en_US
dc.identifier.startpage139en_US
dc.identifier.trdizinid1228184en_US
dc.identifier.urihttps://doi.org/10.5578/flora.202401981
dc.identifier.urihttps://search.trdizin.gov.tr/yayin/detay/1228184
dc.identifier.urihttps://hdl.handle.net/11616/92954
dc.identifier.volume29en_US
dc.identifier.wosWOS:001258696800001en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakTR-Dizinen_US
dc.language.isoenen_US
dc.publisherBilimsel Tip Yayinevien_US
dc.relation.ispartofFlora Infeksiyon Hastaliklari Ve Klinik Mikrobiyoloji Dergisien_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectWordsen_US
dc.subjectPneumocystis jiroveciien_US
dc.subjectClindamycinen_US
dc.subjectCaspofunginen_US
dc.titleTreatment of Pneumocystis jirovecii Pneumonia with Caspofungin and Clindamycin: An HIV Patient and Literature Reviewen_US
dc.typeArticleen_US

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