An evaluation of risk factors, clinical features, andfollow-up findings of patients with infective endocarditis

dc.contributor.authorÖncül, Mehmet
dc.contributor.authorKarakurt, Cemşit
dc.contributor.authorElkıran, Özlem
dc.date.accessioned2024-08-04T19:42:39Z
dc.date.available2024-08-04T19:42:39Z
dc.date.issued2021
dc.departmentİnönü Üniversitesien_US
dc.description.abstractAim: Infective endocarditis (IE) is a serious infection of the endocardial layer of the heart and the endothelial layer of the aorta, which usually is caused by bacteria or fungal microorganisms, requiring early diagnosis and treatment. Congenital heart diseases (CHD) and acquired valvular diseases are risk factors for IE. Advances in life-saving medical interventions such as intensive care, immunosuppressive treatments and the more frequent use of implanted prosthetic materials have increased the risk of IE. The aim of this retrospective study is to evaluate the underlying risk factors, clinical and laboratory findings, microbiological profiles, treatments, and follow-up of patients diagnosed with IE in our clinic. Material and Methods: In this retrospective study, risk factors, clinical features, laboratory findings, microbiological characteristics, echocardiographic features and medical treatment results and complications of 7 patients who admitted to Inonu University Faculty of Medicine Pediatric Cardiology Department a diagnosed with IE, between 2013-2019 were evaluated. Results: Seven patients who were diagnosed with IE were detected from the hospital data system. When the predisposing causes were examined, we found that 3 patients had mitral insufficiency due to rheumatic heart disease, and 3 patients had CHD. None of our patients had a history of intervention before infective endocarditis. Bacteria grew in blood cultures of all patients. The most grown microorganisms were Staphylococci. Surgical treatment, valve repair or replacement therapy, was applied to three patients. A patient, who had aortic coarctation and mycotic aneurysm developing based on infective endarteritis, died on the 5th day due to aneurysm rupture while waiting for surgery under antibiotic pressure. Conclusion: Despite advancing treatment modalities, the mortality rate is about 25%, which is still too high. The most common bacterial infections that cause IE are Streptococci and Staphylococcal infections. Since mortality and morbidity rates are too high in IE, in case of suspicion, necessary laboratory tests and blood cultures should be taken, and treatment should be started immediately.en_US
dc.identifier.doi10.5455/annalsmedres.2021.04.307
dc.identifier.endpage2219en_US
dc.identifier.issn2636-7688
dc.identifier.issue12en_US
dc.identifier.startpage2213en_US
dc.identifier.trdizinid514700en_US
dc.identifier.urihttps://doi.org/10.5455/annalsmedres.2021.04.307
dc.identifier.urihttps://search.trdizin.gov.tr/yayin/detay/514700
dc.identifier.urihttps://hdl.handle.net/11616/88558
dc.identifier.volume28en_US
dc.indekslendigikaynakTR-Dizinen_US
dc.language.isoenen_US
dc.relation.ispartofAnnals of Medical Researchen_US
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.titleAn evaluation of risk factors, clinical features, andfollow-up findings of patients with infective endocarditisen_US
dc.typeArticleen_US

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