Liver transplantation in Turkey: historical review and future perspectives

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dc.authoridAkbulut, Sami/0000-0002-6864-7711
dc.authoridYilmaz, Sezai/0000-0002-8044-0297
dc.authorwosidAkbulut, Sami/L-9568-2014
dc.authorwosidYilmaz, Sezai/ABI-2323-2020
dc.contributor.authorAkbulut, Sami
dc.contributor.authorYilmaz, Sezai
dc.date.accessioned2024-08-04T20:41:17Z
dc.date.available2024-08-04T20:41:17Z
dc.date.issued2015
dc.departmentİnönü Üniversitesien_US
dc.description.abstractSince the first successful liver transplantation by Starzl et al. in 1967, liver transplantation has become the standard therapy for many liver diseases, mainly chronic liver disease. Most liver transplantations performed in Europe and North America utilize deceased donors while a considerable portion of organ requirements is supplied by living donors in Asian countries including Turkey. The actual history of solid organ transplantation in Turkey began with the pioneering work of Dr. Haberal in collaboration with Thomaz E. Starzl in 1974 in Colorado University at Denver. The first successful solid organ transplantation in Turkey was accomplished by Haberal in 1975 with a living donor renal transplantation. Subsequently, legislations no 2238 and 2594 dated 1979 and 1982, respectively, were passed, paving the way for cadaveric tissue/organ utilization and preservation in Turkey. The first deceased donor liver transplantation and the first living donor liver transplantation were performed in 1988 and 1990, respectively. There are currently 45 liver transplantation centers in Turkey. Of these, 25 are state universities, 8 are private (foundation) universities, 9 are private hospitals, and 3 are training and research hospitals belonging to the Ministry of Health. A total of 7152 liver transplantations were performed in Turkey between January 2002 and May 2014. Of these, 4848(67.8%) used living donors and 2304(322%) used deceased donors. These figures indicate that, despite widespread organ donation campaigns and media-sponsored propaganda, desired targets have not been met yet in providing deceased organ donation. Despite unsatisfactory levels attained in supplying deceased donors, both the number of annual liver transplantations and improvements in overall survival rates of organ transplanted patients continues to increase. Actually, the one-year patient survival rate after liver transplantation in 2013 was 80.5%. This rate is getting better with each passing year and believed to be close to 90% in the next few years. (C) 2014 Elsevier Inc. All rights reserved.en_US
dc.identifier.doi10.1016/j.trre.2014.12.002
dc.identifier.endpage167en_US
dc.identifier.issn0955-470X
dc.identifier.issue3en_US
dc.identifier.pmid25535023en_US
dc.identifier.scopus2-s2.0-84945467797en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage161en_US
dc.identifier.urihttps://doi.org/10.1016/j.trre.2014.12.002
dc.identifier.urihttps://hdl.handle.net/11616/97028
dc.identifier.volume29en_US
dc.identifier.wosWOS:000356635000009en_US
dc.identifier.wosqualityQ1en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherElsevier Science Incen_US
dc.relation.ispartofTransplantation Reviewsen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectLiving-Donoren_US
dc.subjectKidney-Transplantationen_US
dc.subjectCyclosporin-Aen_US
dc.subjectHomotransplantationen_US
dc.subjectAdulten_US
dc.subjectPreservationen_US
dc.subjectGraften_US
dc.subjectHomograftsen_US
dc.subjectDonationen_US
dc.titleLiver transplantation in Turkey: historical review and future perspectivesen_US
dc.typeArticleen_US

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