The CHA2DS2-VASc risk score predicts successful endovascular treatment in patients with acute ischemic stroke

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dc.authoridÇakmak, Tolga/0000-0002-4981-5521
dc.authoridYaşar, Erdoğan/0000-0001-5882-3534
dc.authorwosidÇakmak, Tolga/AAN-6803-2021
dc.authorwosidYaşar, Erdoğan/GOH-1219-2022
dc.contributor.authorYasar, Erdogan
dc.contributor.authorAkalin, Yahya
dc.contributor.authorAktas, Ibrahim
dc.contributor.authorCakmak, Tolga
dc.contributor.authorKarakus, Yasin
dc.contributor.authorBayramoglu, Adil
dc.date.accessioned2024-08-04T20:50:53Z
dc.date.available2024-08-04T20:50:53Z
dc.date.issued2022
dc.departmentİnönü Üniversitesien_US
dc.description.abstractObjectives Acute ischemic stroke is a common cause of mortality and morbidity worldwide. Percutaneous endovascular intervention is an important treatment method in ischemic stroke. Endovascular procedure success is associated with the clinical outcome of the patients. The CHA2DS2-VASC score is an important score used to determine the risk of ischemic stroke in patients with atrial fibrillation. In our study, we aimed to evaluate the relationship between procedure success and CHA2DS2-VASC score in patients with acute ischemic stroke who underwent endovascular intervention. Materials and methods A total of 102 consecutive patients who underwent endovascular intervention with acute ischemic stroke were included in the study. The admission CHA2DS2-VASc scores of the patients were recorded. After the procedure, the relationship between the TICI score and the CHA2DS2-VASc score was evaluated. Results CHA2DS2-VASc score was significantly higher in the group that resulted in unsuccessful endovascular intervention (2.78 +/- 1.44, 5.02 +/- 1.77 p < .001). Receiver-operating characteristics analysis revealed the cutoff value of CHA2DS2-VASc score >= 3 as a predictor of unsuccessful intervention with 76,6% sensitivity and 83,3% specificity, positive predictive value 50%, negative predictive value 84,6% (area under the curve [AUC]: 0.827,95% CI: 0.739-0.895, p < .001). In the multivariate analysis; atrial fibrillation ([beta] = 4.201; [CI]: 1.251-14.103, p = .020), CHA2DS2-VASc score ([beta] = 0.053; [CI]: 0.004-0.750, p = .030) were found independent predictors for unsuccessful intervention treatment. Conclusions In our study, we showed that the CHA2DS2-VASc score is associated with the success of endovascular intervention in patients with acute ischemic stroke who underwent percutaneous endovascular treatment.en_US
dc.identifier.doi10.1111/ane.13564
dc.identifier.endpage413en_US
dc.identifier.issn0001-6314
dc.identifier.issn1600-0404
dc.identifier.issue4en_US
dc.identifier.pmid34862802en_US
dc.identifier.scopus2-s2.0-85120481761en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage407en_US
dc.identifier.urihttps://doi.org/10.1111/ane.13564
dc.identifier.urihttps://hdl.handle.net/11616/100339
dc.identifier.volume145en_US
dc.identifier.wosWOS:000726312000001en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherWileyen_US
dc.relation.ispartofActa Neurologica Scandinavicaen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectacute ischemic strokeen_US
dc.subjectCHA2DS2-VASc scoreen_US
dc.subjectendovascular treatmenten_US
dc.titleThe CHA2DS2-VASc risk score predicts successful endovascular treatment in patients with acute ischemic strokeen_US
dc.typeArticleen_US

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