Effect of troponin I and coagulation parameters on mortality in COVID-19 patients

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dc.authoridBULUT, NILUFER/0000-0003-2263-1017
dc.authorwosidBULUT, Nilüfer/HJH-8128-2023
dc.contributor.authorDag, Meral
dc.contributor.authorBulut, Nilufer
dc.contributor.authorTaskapan, M. Cagatay
dc.date.accessioned2024-08-04T20:54:30Z
dc.date.available2024-08-04T20:54:30Z
dc.date.issued2023
dc.departmentİnönü Üniversitesien_US
dc.description.abstractObjective: Our aim is to determine the levels of troponin-I and some coagulation markers (D-dimer, fibrinogen and International Normalized Ratio (INR)) in coronavirus disease 2019 (COVID-19) patients and to investigate the effects of these markers on mortality.Patients and Method: It is planned as a descriptive, cross-sectional and analytical study. The study was conducted by retrospectively scanning the files of COVID-19 patients who applied to Inonu University Turgut Ozal Medical Center between 01.03.2020 and 31.12.2020. Levels of cardiac troponin I markers and coagulation parameters (D-dimer, fibrinogen and INR) were detected.Results: The results of a total of 1858 patients were obtained. One thousand, three hundred and twenty-six patients with only troponin I and D-dimer results (Group 1), 606 patients with only troponin I and fibrinogen results (Group 2), and 1308 patients with only troponin I and INR results (Group 3) were included. Troponin I levels were significantly higher in all patients who died. 96.6% of the patients with high D-dimer levels died in Group 1, 85.5% of the patients with high fibrinogen levels died in Group 2 and 77.3 % of the patients with high INR levels died in Group 3.Conclusion: Measurements of troponin-I and coagulation markers such as D-dimer, fibrinogen and INR can help predict clinical severity and mortality in COVID-19 patients.en_US
dc.identifier.doi10.5472/marumj.1235703
dc.identifier.endpage139en_US
dc.identifier.issn1309-9469
dc.identifier.issue1en_US
dc.identifier.scopus2-s2.0-85164263692en_US
dc.identifier.scopusqualityQ4en_US
dc.identifier.startpage133en_US
dc.identifier.urihttps://doi.org/10.5472/marumj.1235703
dc.identifier.urihttps://hdl.handle.net/11616/101455
dc.identifier.volume36en_US
dc.identifier.wosWOS:000926968200020en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherMarmara Univ, Fac Medicineen_US
dc.relation.ispartofMarmara Medical Journalen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectCOVID-19en_US
dc.subjectTroponin Ien_US
dc.subjectCoagulation markersen_US
dc.subjectD-dimeren_US
dc.subjectFibrinogenen_US
dc.subjectInternational Normalized Ratioen_US
dc.titleEffect of troponin I and coagulation parameters on mortality in COVID-19 patientsen_US
dc.typeArticleen_US

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