Is there a relationship between Toxoplasma gondii infection and idiopathic Parkinson's disease?

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dc.authoridKamisli, Ozden/0000-0003-1114-7860
dc.authoridKamisli, Ozden/0000-0003-1114-7860
dc.authoridGökmen, Derya/0000-0001-6266-3035
dc.authoridcevik, muhammer ozgur/0000-0002-0963-7097
dc.authoridBabur, Cahit/0000-0002-6524-3260
dc.authorwosidKamisli, Ozden/AAA-6553-2020
dc.authorwosidKamisli, Ozden/JVZ-0145-2024
dc.authorwosidGökmen, Derya/JPK-8351-2023
dc.authorwosidcevik, muhammer ozgur/S-7790-2016
dc.contributor.authorCelik, Tuncay
dc.contributor.authorKamisli, Ozden
dc.contributor.authorBabur, Cahit
dc.contributor.authorCevik, Muhammer Ozgur
dc.contributor.authorOztuna, Derya
dc.contributor.authorAltinayar, Sibel
dc.date.accessioned2024-08-04T20:32:26Z
dc.date.available2024-08-04T20:32:26Z
dc.date.issued2010
dc.departmentİnönü Üniversitesien_US
dc.description.abstractIdiopathic Parkinson's disease defines a group of Parkinson's disease (PD) of which the aetiology is unknown but an underlying brain disease is suspected. We selected patients of this subgroup of PD and investigated the seropositivity rate for anti-Toxoplasma IgG antibody by Sabin-Feldman dye test (SFDT). By measuring seropositivity in PD patients, we searched for a probable relationship between Toxoplasma gondii infection and idiopathic PD incidence. Fifty patients diagnosed with idiopathic PD and 50 healthy volunteers were included in the study. Blood samples were taken from all 100 participants and anti-T. gondii antibody titres were investigated using SFDT. Anti-T. gondii antibodies were detected at a titre of >= 1/16 in 25 of the 50 patients (50%) and in 20 of the control group (40%). No higher antibody titre was found in the control group. In conclusion, despite the emerging literature on a possible relationship between T. gondii infection and neurological disease, and the high anti-T. gondii seropositivity found in our PD patients, we did not detect any statistically significant association between T. gondii and idiopathic PD.en_US
dc.identifier.doi10.3109/00365541003716500
dc.identifier.endpage608en_US
dc.identifier.issn0036-5548
dc.identifier.issue8en_US
dc.identifier.pmid20380545en_US
dc.identifier.scopus2-s2.0-77954212167en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage604en_US
dc.identifier.urihttps://doi.org/10.3109/00365541003716500
dc.identifier.urihttps://hdl.handle.net/11616/95072
dc.identifier.volume42en_US
dc.identifier.wosWOS:000281041300007en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherInforma Healthcareen_US
dc.relation.ispartofScandinavian Journal of Infectious Diseasesen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectBehavioren_US
dc.subjectPersonalityen_US
dc.subjectMiceen_US
dc.subjectOriginen_US
dc.subjectHosten_US
dc.titleIs there a relationship between Toxoplasma gondii infection and idiopathic Parkinson's disease?en_US
dc.typeArticleen_US

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