Single intrathecal fentanyl for combined spinal epidural anesthesia confers no advantage over hemodynamic effects in elderly patients

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dc.authoridGulhas, Nurcin/0000-0002-2539-9017
dc.authoridaydogan, mustafa said/0000-0002-7106-1156
dc.authoridErsoy, Mehmet/0000-0002-0724-2825
dc.authoridYücel, Aytaç/0000-0003-0270-8339
dc.authorwosidErdogan, Mehmet Ali/ABI-7224-2020
dc.authorwosidGulhas, Nurcin/A-7281-2018
dc.authorwosidaydogan, mustafa said/AAA-2828-2021
dc.authorwosidErsoy, Mehmet/ACN-2779-2022
dc.authorwosidYücel, Aytaç/ABI-6137-2020
dc.contributor.authorYucel, A.
dc.contributor.authorGulhas, N.
dc.contributor.authorAydogan, M. S.
dc.contributor.authorErdogan, M. A.
dc.contributor.authorBeytur, A.
dc.contributor.authorTasdemir, C.
dc.contributor.authorErsoy, M. O.
dc.date.accessioned2024-08-04T20:35:51Z
dc.date.available2024-08-04T20:35:51Z
dc.date.issued2012
dc.departmentİnönü Üniversitesien_US
dc.description.abstractBackground: Neuroaxial blockade for ambulatory transurethral resection of the prostate is a well established technique. Patients in this group are often at high risk for perioperative complications from concurrent diseases. The purpose of this study was to compare the elderly patients who received intrathecal fentanyl alone or intrathecal fentanyl plus bupivacaine or epidural anesthesia for transurethral resection of prostate surgery. Material and Methods: Ninety-nine patients were prospectively randomized to receive fentanyl 25 mu g (Group F), fentanyl 25 mu g plus hyperbaric bupivacaine 2.5 mg (Group BF), or epidural anesthesia adding fentanyl 50 mu g (Group E) by combined spinal epidural anesthesia technique. Results: The amount of local anesthetics used until when the sensorial block reached the level of T10 was significantly lower in the Group BF than in the Group E and the Group F (p < 0.001). Maximum level of sensory block was significantly lower in the Group BF than in the Group E and the Group F (p = 0.01). The time elapsed until the sensory block reached T10, the regression of sensory block to L5 level were significantly lower in the Group BF than in the Group E and the Group F (p = 0.005, p < 0.001, respectively). Compared to the basal values, mean arterial pressures were significantly lower in the Group BF than in the Group E and the Group F (p < 0.05). The occurrence of hypotension was significantly lower in the Group BF (9.4%) than in the Group E (18.2%) and the Group F (24.2%). Conclusions: Intrathecal hyperbaric bupivacaine 2.5 mg plus fentanyl 25 mu g administration provides shorter motor block onset time, less local anesthetic usage and adequate hemodynamic stability in elderly patients.en_US
dc.identifier.endpage212en_US
dc.identifier.issn1128-3602
dc.identifier.issue2en_US
dc.identifier.pmid22428471en_US
dc.identifier.scopus2-s2.0-84859515259en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage207en_US
dc.identifier.urihttps://hdl.handle.net/11616/95616
dc.identifier.volume16en_US
dc.identifier.wosWOS:000301317000008en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherVerduci Publisheren_US
dc.relation.ispartofEuropean Review For Medical and Pharmacological Sciencesen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectHemodynamic effectsen_US
dc.subjectNeuroaxial blockadeen_US
dc.subjectSpinal epiduralen_US
dc.subjectAnesthesiaen_US
dc.titleSingle intrathecal fentanyl for combined spinal epidural anesthesia confers no advantage over hemodynamic effects in elderly patientsen_US
dc.typeArticleen_US

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