Comparison of the Anesthetic Efficiency of Lidocaine and Tramadol Hydrochloride in Orthodontic Extractions: A Split-Mouth, Prospective, Randomized, Double-Blind Study

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dc.authoridEGE, MIRAY/0000-0002-8872-5983
dc.authorwosidEge, Bilal/S-3891-2016
dc.authorwosidalan, hilal/ABH-9301-2020
dc.authorwosidEge, Miray/AAU-7477-2020
dc.contributor.authorEge, Bilal
dc.contributor.authorEge, Miray
dc.contributor.authorKoparal, Mahmut
dc.contributor.authorAlan, Hilal
dc.date.accessioned2024-08-04T20:46:45Z
dc.date.available2024-08-04T20:46:45Z
dc.date.issued2020
dc.departmentİnönü Üniversitesien_US
dc.description.abstractPurpose: The aim of the present randomized controlled split-mouth clinical study was to evaluate and compare the clinical anesthetic efficacy of lidocaine and tramadol hydrochloride in orthodontic extractions. Materials and Methods: A total of 32 systemically healthy patients requiring bilaterally maxillary first premolar extractions for orthodontic reasons were included. Each patient received 1.8 mL of lidocaine (36 mg lidocaine HCI and 0.0225 mg epinephrine) on 1 side and 1.8 mL tramadol (50 mg tramadol HCl and 0.0225 mg epinephrine diluted to 1.8 mL by distilled water) on the other side. The anesthetic solutions were infiltrated into the buccal vestibule (local infiltration) based on a computer-generated list. In each patient, the time of anesthetic onset and finish, anesthetic activity, duration of postoperative analgesia, additional analgesic medication, wound healing, possible side effects, and satisfaction levels were recorded intraoperatively and postoperatively for both sides. Results: Although no relevant differences were found between the solutions for anesthetic onset, lidocaine was significantly more effective statistically for the total anesthesia duration. Comparing the anesthetic activity at 5 minutes before extraction, we found that tramadol was significantly more effective statistically compared with lidocaine. Similarly, tramadol was significantly more effective statistically than lidocaine for satisfaction level and wound healing. Moreover, compared with tramadol, in terms of postoperative pain, the visual analog scale scores with lidocaine were significantly higher at statistically 7, 8, 9, and 10 hours during the first 12 hours. In general, the lidocaine values were dramatically higher than were the tramadol values. Conclusions: The results of the present study suggest that using tramadol combined with epinephrine can be an alternative local anesthetic for maxillary first premolar tooth extractions in oral-maxillofacial surgery. (C) 2019 American Association of Oral and Maxillofacial Surgeonsen_US
dc.identifier.doi10.1016/j.joms.2019.07.010
dc.identifier.endpage62en_US
dc.identifier.issn0278-2391
dc.identifier.issn1531-5053
dc.identifier.issue1en_US
dc.identifier.pmid31454502en_US
dc.identifier.scopus2-s2.0-85071719863en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage52en_US
dc.identifier.urihttps://doi.org/10.1016/j.joms.2019.07.010
dc.identifier.urihttps://hdl.handle.net/11616/98939
dc.identifier.volume78en_US
dc.identifier.wosWOS:000504757500012en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherW B Saunders Co-Elsevier Incen_US
dc.relation.ispartofJournal of Oral and Maxillofacial Surgeryen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectPreventing Postoperative Painen_US
dc.subject3rd Molar Surgeryen_US
dc.subjectAnalgesic Efficacyen_US
dc.subjectMandibular 3rd-Molaren_US
dc.subjectMeperidineen_US
dc.subjectMepivacaineen_US
dc.subjectPrilocaineen_US
dc.subjectArticaineen_US
dc.subjectFentanylen_US
dc.titleComparison of the Anesthetic Efficiency of Lidocaine and Tramadol Hydrochloride in Orthodontic Extractions: A Split-Mouth, Prospective, Randomized, Double-Blind Studyen_US
dc.typeArticleen_US

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