Retrospective assessment of our anesthesia practice for electroconvulsive therapy
Küçük Resim Yok
Tarih
2008
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Aim: Electroconvulsive therapy (ECT) is a treatment method of some psychiatric disorders which is based on to form seizure activity by electrical stimulus. The aim of this retrospective study was to evaluate anesthetic agents which were used, the duration of seizure activity and recovery times, hemodynamic changes and the complications of the procedure in patients underwent ECT in our clinic. Materials and Methods: The anesthesia records of 460 ECT procedures performed in our clinic between October 2002-April 2007 were analyzed retrospectively. Patients were allocated to receive propofol 1 mg kg -1 after dexmedetomidine (1 ?g kg-1 h-1, 10 min.) premedication (Group 1); propofol 1,2 mg kg-1 (Group 2); propofol 1,5 mg kg-1 (Group 3); or sevoflurane 7 % (Group 4) without premedication as an induction agent. Results: Mean duration of motor seizure was 39.06±10.79 s. in Group 4, significantly longer than Group 1 and 3. Mean duration of motor seizure was 29.78±7.85 min in Group 3 significantly shorter than Group 2 (p<0.05). Duration of response to verbal stimulus in Group 3 and 4 were longer than Group 1 and 2 (p<0.05). Heart rate was lower in Group 1 compare from baseline value after convulsion at 1. and 10. min (p<0.05). Mean arterial pressure was lower at 10 min after convulsion in Group 1 and 3; at 1. and 10 min after convulsion in Group 4 (p<0.05). Conclusion: We determined that sevoflurane (7 %), 1,2-1,5 mg kg-1 dose of propofol and premedication with dexmedctomidine 1 ? kg-1 h-1 (10 min) prevent acute hemodynamic response to ECT without decreasing the duration of seizure. However, further studies of dexmedetomidine safety and interactions with other drugs are required before recommendation of its use for ECT procedures.
Açıklama
Anahtar Kelimeler
Dexmedetomidine, Electroconvulsive therapy, Propofol, Sevoflurane
Kaynak
Turk Anesteziyoloji ve Reanimasyon Dernegi Dergisi
WoS Q Değeri
Scopus Q Değeri
N/A
Cilt
36
Sayı
4
