The effect of thrombocytapheresis on hemogram and biochemistry parameters in patients with essential thrombocytemia

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dc.authoridSARICI, Ahmet/0000-0002-5916-0119
dc.authoridYagin, Fatma Hilal/0000-0002-9848-7958
dc.authorwosidSARICI, Ahmet/ABI-7512-2020
dc.authorwosidYagin, Fatma Hilal/ABI-8066-2020
dc.contributor.authorKaya, Ahmet
dc.contributor.authorKuku, Irfan
dc.contributor.authorErkurt, Mehmet Ali
dc.contributor.authorKaya, Emin
dc.contributor.authorBerbera, Ilhami
dc.contributor.authorBicim, Soykan
dc.contributor.authorHidayet, Emine
dc.date.accessioned2024-08-04T20:54:37Z
dc.date.available2024-08-04T20:54:37Z
dc.date.issued2023
dc.departmentİnönü Üniversitesien_US
dc.description.abstractBackground: Essential thrombocythemia is one of the chronic myeloproliferative neoplasms characterized by clonal proliferation of myeloid cells with variable morphological maturation and hematopoietic activity. It is characterized by excessive clonal platelet production with a tendency to thrombosis and bleeding. Thrombocytapherests is the removal of platelets by apheresis techniques. Thrombocytapherests is generally recommended in patients with essential thrombocythemia with acute, severe thrombotic or hemorrhagic events.Methods: The study included 39 patients who were diagnosed with essential thrombocythemia, started cytoreductive and aspirin therapy, and underwent thrombocytapherests due to the development of acute severe thrombotic or hemorrhagic events, diagnosed in the adult hematology clinic of I_nonu University Turgut Ozal Medical Center. Hemogram and biochemistry values of the patients were scanned retrospectively.Results: After thrombocytapherests, a statistically significant difference was found between the first and last measurements of hemoglobin, mean platelet volume, White blood cell, neutrophil, platelet, platelet distribution width, creatine, lactate dehydrogenase, fibronogen and calcium levels of the patients. Conclusion: The use of thrombocytapherests in patients with essential thrombocytosis causes a rapid decrease in platelet values as well as an effect on hemogram and biochemistry parameters. Other hemogram and biochemistry parameters such as platelet value should be monitored in patients.(c) 2023 Societe francaise de transfusion sanguine (SFTS). Published by Elsevier Masson SAS. All rights reserved.en_US
dc.identifier.doi10.1016/j.tracli.2023.08.001
dc.identifier.endpage425en_US
dc.identifier.issn1246-7820
dc.identifier.issue4en_US
dc.identifier.pmid37558046en_US
dc.identifier.scopus2-s2.0-85168356638en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage421en_US
dc.identifier.urihttps://doi.org/10.1016/j.tracli.2023.08.001
dc.identifier.urihttps://hdl.handle.net/11616/101524
dc.identifier.volume30en_US
dc.identifier.wosWOS:001101825900001en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherElsevier France-Editions Scientifiques Medicales Elsevieren_US
dc.relation.ispartofTransfusion Clinique Et Biologiqueen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectEssential thrombocythemiaen_US
dc.subjectThrombocytapheresisen_US
dc.subjectHemogramen_US
dc.subjectBiochemistryen_US
dc.titleThe effect of thrombocytapheresis on hemogram and biochemistry parameters in patients with essential thrombocytemiaen_US
dc.typeArticleen_US

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