An international survey on hypoglycemia among insulin-treated type I and type II diabetes patients: Turkey cohort of the non-interventional IO HAT study

dc.authoridSahin, Ibrahim/0000-0002-6231-0034
dc.authoridTütüncü, Neslihan Başçıl/0000-0002-1816-3903;
dc.authorwosidemral, rıfat/AAH-1386-2020
dc.authorwosidSahin, Ibrahim/ABI-6050-2020
dc.authorwosidTütüncü, Neslihan Başçıl/ABG-5027-2020
dc.authorwosidŞahin, İbrahim/HHY-8303-2022
dc.authorwosidEmral, Rıfat/AAA-9097-2021
dc.contributor.authorEmral, Rifat
dc.contributor.authorTetiker, Tamer
dc.contributor.authorSahin, Ibrahim
dc.contributor.authorSari, Ramazan
dc.contributor.authorKaya, Ahmet
dc.contributor.authorYetkin, Ilhan
dc.contributor.authorCil, Sefika Uslu
dc.date.accessioned2024-08-04T20:44:17Z
dc.date.available2024-08-04T20:44:17Z
dc.date.issued2018
dc.departmentİnönü Üniversitesien_US
dc.description.abstractBackground: Limited real-world data are currently available on hypoglycemia in diabetes patients. The International Operations Hypoglycemia Assessment Tool (IO HAT) study was designed to estimate hypoglycemia in insulin-treated type I (T1DM) and type II (T2DM) diabetes mellitus patients from 9 countries. The data from Turkey cohort are presented here. Methods: A non-interventional study to determine the hypoglycemia incidence, retrospectively and prospectively, in Turkish T1DM and T2DM patients using a 2-part self-assessment questionnaire. Results: Overall, 2348 patients were enrolled in the Turkey cohort (T1DM = 306 patients, T2DM = 2042 patients). In T1DM patients, 96.8% patients reported hypoglycemic events (Incidence rate [IR]: 68.6 events per patient-year [ppy]), prospectively, while 74.0% patients reported hypoglycemic events (IR: 51.7 events ppy), retrospectively. In T2DM patients, 95.9% patients (IR: 28.3 events ppy) reported hypoglycemic events, prospectively, while 53.6% patients (IR: 23.0 events ppy) reported hypoglycemic events, retrospectively. Nearly all patients reported hypoglycemia during the prospective period. Conclusions: This is a first patient-reported dataset on hypoglycemia in Turkish, insulin-treated diabetes patients. A high incidence of patient-reported hypoglycemia confirms that hypoglycemia remains under-estimated. Hypoglycemia increased healthcare utilization impacting patients' quality of life. Hypoglycemia remains a common side effect with insulin-treatment and strategies to optimize therapy and reduce hypoglycemia occurrence in diabetes patients are required.en_US
dc.description.sponsorshipNovo Nordisken_US
dc.description.sponsorshipFinancial support for the conduct of the research was provided by Novo Nordisk.en_US
dc.identifier.doi10.1186/s12902-018-0238-2
dc.identifier.issn1472-6823
dc.identifier.pmid29433560en_US
dc.identifier.scopus2-s2.0-85041858991en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.urihttps://doi.org/10.1186/s12902-018-0238-2
dc.identifier.urihttps://hdl.handle.net/11616/98152
dc.identifier.volume18en_US
dc.identifier.wosWOS:000425180000001en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherBmcen_US
dc.relation.ispartofBmc Endocrine Disordersen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectDiabetesen_US
dc.subjectTurkeyen_US
dc.subjectHypoglycemiaen_US
dc.subjectIO HATen_US
dc.subjectInsulinen_US
dc.subjectNon-interventionalen_US
dc.titleAn international survey on hypoglycemia among insulin-treated type I and type II diabetes patients: Turkey cohort of the non-interventional IO HAT studyen_US
dc.typeArticleen_US

Dosyalar