Clinical Characteristics and Outcomes of Cancer Cases Among Syrian Refugees From Southern Turkey

Basit Öğe Kaydı
dc.authoridAhmed, Fahad/0000-0001-9337-4308
dc.authoridokan, vahap/0000-0002-9869-8181
dc.authoridSullivan, Richard/0000-0002-6435-1825
dc.authorwosidAhmed, Fahad/AFO-7477-2022
dc.authorwosidAkbayram, Sinan/AAG-5737-2020
dc.authorwosidokan, vahap/AAH-1424-2020
dc.authorwosidYalcin, Suayib/KWT-7106-2024
dc.authorwosidAyyildiz, Orhan/AEO-2377-2022
dc.authorwosidSullivan, Richard/JQV-9587-2023
dc.contributor.authorKutluk, Tezer
dc.contributor.authorSahin, Berksoy
dc.contributor.authorKirazli, Meral
dc.contributor.authorAhmed, Fahad
dc.contributor.authorAydin, Sinem
dc.contributor.authorCinkir, Havva Yesil
dc.contributor.authorSezgin, Guelay
dc.date.accessioned2024-08-04T20:53:44Z
dc.date.available2024-08-04T20:53:44Z
dc.date.issued2023
dc.departmentİnönü Üniversitesien_US
dc.description.abstractImportance Cancer was a common noncommunicable disease in Syria before the present conflict and is now a major disease burden among 3.6 million Syrian refugees in Turkey. Data to inform health care practice are needed. Objective To explore sociodemographic characteristics, clinical characteristics, and treatment outcomes of Syrian patients with cancer residing in the southern border provinces of Turkey hosting more than 50% of refugees. Design, Setting, and ParticipantsThis was a retrospective hospital-based cross-sectional study. The study sample consisted of all adult and children Syrian refugees diagnosed and/or treated for cancer between January 1, 2011, and December 31, 2020, in hematology-oncology departments of 8 university hospitals in the Southern province of Turkey. Data were analyzed from May 1, 2022, to September 30, 2022. Main Outcomes and Measures Demographic characteristics (date of birth, sex, and residence), date of first cancer-related symptom, date and place of diagnosis, disease status at first presentation, treatment modalities, date and status at last hospital visit, and date of death. The International Statistical Classification of Diseases and Related Health Problems, Tenth Revision and International Classification of Childhood Cancers, Third Edition, were used for the classification of cancer. The Surveillance, Epidemiology, and End Results system was applied for staging. The diagnostic interval was defined as the number of days from first symptoms until the diagnosis. Treatment abandonment was documented if the patient did not attend the clinic within 4 weeks of a prescribed appointment throughout the treatment. Results A total of 1114 Syrian adult and 421 Syrian children with cancer were included. The median age at diagnosis was 48.2 (IQR, 34.2-59.4) years for adults and 5.7 (IQR, 3.1-10.7) years for children. The median diagnostic interval was 66 (IQR, 26.5-114.3) days for adults and 28 (IQR, 14.0-69.0) days for children. Breast cancer (154 [13.8%]), leukemia and multiple myeloma (147 [13.2%]), and lymphoma (141 [12.7%]) were common among adults, and leukemias (180 [42.8%]), lymphomas (66 [15.7%]), and central nervous system neoplasms (40 [9.5%]) were common among children. The median follow-up time was 37.5 (IQR, 32.6-42.3) months for adults and 25.4 (IQR, 20.9-29.9) months for children. The 5-year survival rate was 17.5% in adults and 29.7% in children. Conclusions and Relevance Despite universal health coverage and investment in the health care system, low survival rates were reported in this study for both adults and children with cancer. These findings suggest that cancer care in refugees requires novel planning within national cancer control programs with global cooperation.en_US
dc.description.sponsorshipUK Research and Innovation GCRF Research for Health in Conflict (R4HC-MENA); developing capability, partnerships and research in the Middle and Near East [ES/P010962/1]; National Institute of Health Research Project GACD R4HSSS grant [NIHR131207]; National Institutes of Health Research (NIHR) [NIHR131207] Funding Source: National Institutes of Health Research (NIHR)en_US
dc.description.sponsorshipThis study was funded through the UK Research and Innovation GCRF Research for Health in Conflict (R4HC-MENA); developing capability, partnerships and research in the Middle and Near East (grant ES/P010962/1). Dr Sullivan is funded by National Institute of Health Research Project GACD R4HSSS grant NIHR131207.en_US
dc.identifier.doi10.1001/jamanetworkopen.2023.12903
dc.identifier.issn2574-3805
dc.identifier.issue5en_US
dc.identifier.pmid37219908en_US
dc.identifier.scopus2-s2.0-85160013024en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.urihttps://doi.org/10.1001/jamanetworkopen.2023.12903
dc.identifier.urihttps://hdl.handle.net/11616/101368
dc.identifier.volume6en_US
dc.identifier.wosWOS:001046640100001en_US
dc.identifier.wosqualityQ1en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherAmer Medical Assocen_US
dc.relation.ispartofJama Network Openen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectHealth-Careen_US
dc.subjectChildrenen_US
dc.subjectJordanen_US
dc.titleClinical Characteristics and Outcomes of Cancer Cases Among Syrian Refugees From Southern Turkeyen_US
dc.typeArticleen_US

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayın Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu