The effect of caffeic acid phenethyl ester on ischemia-reperfusion injury in comparison with ?-tocopherol in rat kidneys

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dc.authoridOZYURT, Huseyin/0000-0003-2327-4082
dc.authoridYAGMURCA, MURAT/0000-0001-9774-8151
dc.authoridIrmak, M. Kemal/0000-0002-1903-8303
dc.authoridKutlu, Nurettin Onur/0000-0002-3306-6570;
dc.authorwosidOZYURT, Huseyin/N-4351-2015
dc.authorwosidYAGMURCA, MURAT/A-1851-2018
dc.authorwosidIrmak, M. Kemal/H-6667-2014
dc.authorwosidYAĞMURCA, Murat/AAH-4496-2019
dc.authorwosidKutlu, Nurettin Onur/AAW-6196-2021
dc.authorwosidKARAMAN, Abdurrahman/G-7825-2016
dc.contributor.authorIrmak, MK
dc.contributor.authorKoltuksuz, U
dc.contributor.authorKutlu, NO
dc.contributor.authorYagmurca, M
dc.contributor.authorÖzyurt, H
dc.contributor.authorKaraman, A
dc.contributor.authorAkyol, Ö
dc.date.accessioned2024-08-04T20:12:16Z
dc.date.available2024-08-04T20:12:16Z
dc.date.issued2001
dc.departmentİnönü Üniversitesien_US
dc.description.abstractOxygen-derived free radicals have been implicated in the pathogenesis of renal injury after ischemia-reperfusion. Caffeic acid phenethyl ester (CAPE), an active component of propolis extract, exhibits antioxidant and anti-inflammatory properties. To determine whether CAPE offers any advantage over alpha -tocopherol, we compared their effects on an in vivo model of renal ischemia-reperfusion injury in rats. CAFE at 10 mu mol/kg or alpha -tocopherol at 10 mg/kg was administered intraperitoneally before reperfusion. Acute administration of CAFE suppressed ischemia-reperfusion induced renal lipid peroxidation and tissue injury more than alpha -tocopherol. CAFE may therefore offer a therapeutic advantage in acute injury settings.en_US
dc.identifier.doi10.1007/s002400100185
dc.identifier.endpage193en_US
dc.identifier.issn0300-5623
dc.identifier.issue3en_US
dc.identifier.pmid11482445en_US
dc.identifier.scopus2-s2.0-0034944281en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage190en_US
dc.identifier.urihttps://doi.org/10.1007/s002400100185
dc.identifier.urihttps://hdl.handle.net/11616/93298
dc.identifier.volume29en_US
dc.identifier.wosWOS:000169632900010en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherSpringer-Verlagen_US
dc.relation.ispartofUrological Researchen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectreperfusion injuryen_US
dc.subjectkidneyen_US
dc.subjectcaffeic acid phenethyl esteren_US
dc.subjectalpha-tocopherolen_US
dc.titleThe effect of caffeic acid phenethyl ester on ischemia-reperfusion injury in comparison with ?-tocopherol in rat kidneysen_US
dc.typeArticleen_US

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