Evaluation of novel ventricular repolarization parameters in patients with acromegaly

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dc.contributor.authorEren, Hayati
dc.contributor.authorGenc, Selin
dc.contributor.authorEvren, Bahri
dc.contributor.authorŞahin, İbrahim
dc.date.accessioned2024-08-04T19:54:34Z
dc.date.available2024-08-04T19:54:34Z
dc.date.issued2023
dc.departmentİnönü Üniversitesien_US
dc.description.abstractObjectives: T wave’s peak and end interval (Tp-e), Tp-e/QT ratio and Tp-e/QTc ratio are novel markers of ventricular repolarization and are associated with ventricular arrhythmias. Increased ventricular arrhythmia incidence is reported in patients with acromegaly. The purpose of this study is to evaluate ventricular repolarization using the Tp-e interval, Tp-e/QT ratio, and Tp-e/QTc ratio in patients with acromegaly. Methods: Thirty-five patients with acromegaly were included in the study. The control group was consisted of forty-one subjects without acromegaly that having similar age, sex ratio and comorbidities. The Tp-e interval, Tp-e/QT ratio, Tp-e/QTc ratio, and other ventricular repolarization parameters of all patients were evaluated using electrocardiography. Results: Tp-e interval, Tp-e/QT ratio and Tp-e/QTc ratio were significantly prolonged in patients with acromegaly compared to the control group. Furthermore, Tp-e interval, Tp-e/QT ratio, and Tp-e/QTc ratio showed a significant correlation with plasma GH levels and LVMI values. Conclusions: Our study revealed that Tp-e interval, Tp-e/QT ratio, and Tp-e/QTc ratio are prolonged in patients with acromegaly. We believe that the Tp-e interval, Tp-e/QT ratio, and Tpe/QTc ratio can be used in the evaluation of increased cardiovascular risk in patients with acromegaly.en_US
dc.identifier.doi10.18621/eurj.1128668
dc.identifier.endpage590en_US
dc.identifier.issn2149-3189
dc.identifier.issue3en_US
dc.identifier.startpage582en_US
dc.identifier.trdizinid1165326en_US
dc.identifier.urihttps://doi.org/10.18621/eurj.1128668
dc.identifier.urihttps://search.trdizin.gov.tr/yayin/detay/1165326
dc.identifier.urihttps://hdl.handle.net/11616/89947
dc.identifier.volume9en_US
dc.indekslendigikaynakTR-Dizinen_US
dc.language.isoenen_US
dc.relation.ispartofThe European Research Journalen_US
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.titleEvaluation of novel ventricular repolarization parameters in patients with acromegalyen_US
dc.typeArticleen_US

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