Left atrial volume and function in patients with Behcet's disease assessed by real-time three-dimensional echocardiography

dc.authoridPekdemir, Hasan/0000-0002-4913-5120
dc.authoridAkaycan, Jülide/0000-0002-9174-6777;
dc.authorwosidPekdemir, Hasan/ABI-6096-2020
dc.authorwosidAKTÜRK, SEMRA/ABI-2757-2020
dc.authorwosidErmis, Necip/A-5184-2018
dc.authorwosidAkaycan, Jülide/ABI-2397-2020
dc.authorwosidErmis, Necip/HJP-7061-2023
dc.authorwosidSener, Serpil/ABI-6229-2020
dc.contributor.authorAkturk, Erdal
dc.contributor.authorYagmur, Julide
dc.contributor.authorKurtoglu, Ertugrul
dc.contributor.authorErmis, Necip
dc.contributor.authorAcikgoz, Nusret
dc.contributor.authorSener, Serpil
dc.contributor.authorKarakus, Yasin
dc.date.accessioned2024-08-04T20:36:10Z
dc.date.available2024-08-04T20:36:10Z
dc.date.issued2012
dc.departmentİnönü Üniversitesien_US
dc.description.abstractAims Behcet's disease (BD), a multisystemic inflammatory disorder, has been associated with a number of cardiovascular dysfunctions, including endomyocardial fibrosis of the right heart, atrial fibrillation, ventricular arrhythmias and sudden cardiac death. The incidence and nature of cardiac involvement in BD are not yet clearly documented. Our aim was to evaluate left atrial (LA) volume and functions using real-time three-dimensional echocardiography (RT3DE) in Behcet's patients without any cardiac symptom. Methods end results The study included 40 BD (16 females, 24 males and mean age of 33 +/- 7 years) and 30 healthy (11 females, 19 males and mean age of 35 +/- 6 years) subjects. All the patients' demographic parameters such as age, gender, and duration of BD were recorded. All the individuals underwent comprehensive 2D echocardiography examination, and RT3DE was performed to assess LA volumes and mechanical functions. LA maximum volume (V-max) and before atrial contraction volume (V, re A) LA active stroke volume and total stroke volumes (TSV), total emptying and active emptying fractions and expansion index were significantly higher in Behcet's disease patients when compared with the controls (P < 0.0001 for all). LA passive emptying fraction was significantly lower in the patients with BD than in the controls (41 +/- 7 vs. 44 +/- 5, P = 0.039). There were positive correlations between TSV and high-sensitive C-reactive protein level (r = 0.413, P = 0.008), TSV, and disease duration (r = 0.417, P < 0.007). Conclusion Our study has shown that LA mechanical functions and volumes are impaired in BD. These results may be an early form of subclinical cardiac involvement in patients with BD who have no clinical evidence for cardiovascular disease.en_US
dc.identifier.doi10.1093/ejechocard/jer301
dc.identifier.endpage655en_US
dc.identifier.issn2047-2404
dc.identifier.issn2047-2412
dc.identifier.issue8en_US
dc.identifier.pmid22271104en_US
dc.identifier.scopus2-s2.0-84866250327en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage650en_US
dc.identifier.urihttps://doi.org/10.1093/ejechocard/jer301
dc.identifier.urihttps://hdl.handle.net/11616/95801
dc.identifier.volume13en_US
dc.identifier.wosWOS:000307146000004en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherOxford Univ Pressen_US
dc.relation.ispartofEuropean Heart Journal-Cardiovascular Imagingen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectBehcet's diseaseen_US
dc.subjectleft atrial volumeen_US
dc.subjectleft atrial functionen_US
dc.subjectreal-time three-dimensional echocardiographyen_US
dc.titleLeft atrial volume and function in patients with Behcet's disease assessed by real-time three-dimensional echocardiographyen_US
dc.typeArticleen_US

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