The Bad Bug is Back: Acinetobacter Baumannii Bacteremia Outbreak during the COVID-19 Pandemic in an Intensive Care Unit

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dc.authorscopusid16245973100
dc.authorscopusid57223049137
dc.authorscopusid6506163298
dc.authorscopusid6602182205
dc.authorscopusid57223832958
dc.authorscopusid57217036684
dc.authorscopusid57210211362
dc.contributor.authorMete B.
dc.contributor.authorKurt A.F.
dc.contributor.authorUrkmez S.
dc.contributor.authorDemirkiran O.
dc.contributor.authorCan G.
dc.contributor.authorDumanli G.Y.
dc.contributor.authorBozbay S.
dc.date.accessioned2024-08-04T20:00:47Z
dc.date.available2024-08-04T20:00:47Z
dc.date.issued2022
dc.departmentİnönü Üniversitesien_US
dc.description.abstractBackground: Epidemiology of nosocomial infections may show variability because of under-estimation of infection control measures (ICMs) in coronavirus disease 19 (COVID-19) outbreak. Aim: To investigate the Acinetobacter bacteremia outbreak developed in an intensive care unit (ICU) between March 20 to May 15, 2020, examine the risk factors, and re-evaluate ICM retrospectively. Material and Methods: A retrospective cohort analysis was conducted to determine the risk factors, pulsed field gel electrophoresis (PFGE) was performed for analysis of the outbreak, ICM practices were observed by a team, and infection control interventions were undertaken. Results: Acinetobacter bacteremia developed in 17 patients (21.5%) within 79 COVID-19 patients included in the study. The mean age of the bacteremic patients was 67.3 (SD = 14.82) years, and 82.4% of them were male; of these, 15 died, leading to 88.2% mortality. The bacteremia rate was higher compared with a 14-month period preceding the COVID-19 pandemic (17/79 versus 12/580 patients, respectively). PFGE revealed that the outbreak was polyclonal. On multi-variate analysis, the bacteremia development rate was 13.7 and 5.06 times higher with central venous catheter (CVC) use and in patients with chronic obstructive pulmonary disease (COPD), respectively. The mortality rate was higher in bacteremic patients (p = 0.0016). It was observed that ICMs were not followed completely, especially change of gloves and hand hygiene. Contamination of A. baumannii was observed in 38% of the gloves. Conclusion: COPD and CVC use were determined as risk factors for Acinetobacter bacteremia development, and failures in ICM may have led to cross-contamination of endemic A. baumannii. The outbreak could be controlled within 3 weeks of interventions. © 2022 Wolters Kluwer Medknow Publications. All rights reserved.en_US
dc.identifier.doi10.4103/njcp.njcp_2001_21
dc.identifier.endpage709en_US
dc.identifier.issn1119-3077
dc.identifier.issue5en_US
dc.identifier.pmid35593616en_US
dc.identifier.scopus2-s2.0-85130864245en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage702en_US
dc.identifier.urihttps://doi.org/10.4103/njcp.njcp_2001_21
dc.identifier.urihttps://hdl.handle.net/11616/91010
dc.identifier.volume25en_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherWolters Kluwer Medknow Publicationsen_US
dc.relation.ispartofNigerian Journal of Clinical Practiceen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAcinetobacter baumanniien_US
dc.subjectCOVID-19en_US
dc.subjectoutbreaken_US
dc.titleThe Bad Bug is Back: Acinetobacter Baumannii Bacteremia Outbreak during the COVID-19 Pandemic in an Intensive Care Uniten_US
dc.typeArticleen_US

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