Relationships between plasma pentraxin 3 levels and inflammation markers patients with tunneled permanent catheter in hemodialysis

Basit Öğe Kaydı
dc.authoridComert, Melda/0000-0002-7798-4349
dc.authoridİLHAN, NECİP/0000-0001-9997-0418
dc.authoridtaskapan, hulya/0000-0001-8736-4779
dc.authorwosidDogukan, Ayhan/W-2518-2018
dc.authorwosidPembegul, Irem/AAB-6645-2022
dc.authorwosidComert, Melda/ABH-5764-2020
dc.authorwosidPembegul, Irem/HJA-2191-2022
dc.authorwosidAygen, Bilge/X-6557-2018
dc.authorwosidulu, ramazan/V-9751-2018
dc.authorwosidİLHAN, NECİP/V-8908-2018
dc.contributor.authorYigit, Irem Pembegul
dc.contributor.authorDogukan, Ayhan
dc.contributor.authorTaskapan, Hulya
dc.contributor.authorComert, Melda
dc.contributor.authorIlhan, Necip
dc.contributor.authorUlu, Ramazan
dc.contributor.authorAygen, Bilge
dc.date.accessioned2024-08-04T20:41:16Z
dc.date.available2024-08-04T20:41:16Z
dc.date.issued2015
dc.departmentİnönü Üniversitesien_US
dc.description.abstractPurpose: Vascular access (VA) devices may contribute to chronic inflammation in hemodialysis (HD). Pentraxin 3 (PTX3) is a recently discovered acute phase protein that responds more rapidly than other inflammatory markers. This study compared PTX3 and other markers between HD patients and healthy controls. Methods: The study population included 30 patients with tunneled permanent catheter (TPC), 30 patients with arteriovenous fistula (AVF) and 30 healthy controls. Hemogram, biochemical assays, ferritin, high sensitive Creactive protein (hs-CRP), tumor necrosis factor-alpha (TNF-alpha) and PTX3 were evaluated in all groups. Results: PTX levels were highest in HD patients with TPC, intermediated in HD patients with AVF and lowest in healthy controls (5.2 + 2.4 vs. 3.1 + 1.3 vs. 1.8 + 0.7, p<0.001 for all comparisons). PTX3 levels correlated strongly to hs-CRP (r = 0.857) and moderately to TNF-alpha, NLR, ferritin and total neutrophil count. PTX3 and albumin levels had a negative correlation. PTX3 levels were higher in patients with 8 months of TPC than those with 7 months or less. Conclusions: PTX3 levels are significantly elevated in all patients on HD, but presence and extended duration of TPC are associated with incrementally higher levels of PTX3 and other inflammatory markers. PTX3 and NLR may be useful in assessing chronic inflammatory states in HD.en_US
dc.description.sponsorshipFirat University Scientific Research Foundationen_US
dc.description.sponsorshipThis study was supported by Firat University Scientific Research Foundation.en_US
dc.identifier.doi10.5301/jva.5000409
dc.identifier.endpage381en_US
dc.identifier.issn1129-7298
dc.identifier.issn1724-6032
dc.identifier.issue5en_US
dc.identifier.pmid26070095en_US
dc.identifier.scopus2-s2.0-84943236088en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage377en_US
dc.identifier.urihttps://doi.org/10.5301/jva.5000409
dc.identifier.urihttps://hdl.handle.net/11616/97003
dc.identifier.volume16en_US
dc.identifier.wosWOS:000366487400015en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherWichtig Publen_US
dc.relation.ispartofJournal of Vascular Accessen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectArteriovenous fistulaen_US
dc.subjectHemodialysisen_US
dc.subjectInflammationen_US
dc.subjectPentraxin 3en_US
dc.subjectTunneled permanent catheteren_US
dc.titleRelationships between plasma pentraxin 3 levels and inflammation markers patients with tunneled permanent catheter in hemodialysisen_US
dc.typeArticleen_US

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayın Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu