Systolic aortic root motion predicts response to cardiac resynchronization therapy

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dc.authoridACAR, BURAK/0000-0003-3217-5000
dc.authoridHidayet, Şıho/0000-0002-4103-9345
dc.authoridCelikyurt, Umut/0000-0003-4957-7102
dc.authorwosidACAR, BURAK/ABD-9011-2021
dc.authorwosidAcar, Burak/GVT-1660-2022
dc.authorwosidKaraüzüm, İrem/GXW-0700-2022
dc.authorwosidCelikyurt, Umut/AAG-2320-2021
dc.authorwosidHidayet, Şıho/ABI-2256-2020
dc.contributor.authorCelikyurt, Umut
dc.contributor.authorAcar, Burak
dc.contributor.authorHidayet, Siho
dc.contributor.authorKarauzum, Irem
dc.contributor.authorKarauzum, Kurtulus
dc.contributor.authorVural, Ahmet
dc.contributor.authorAgacdiken, Aysen
dc.date.accessioned2024-08-04T20:46:45Z
dc.date.available2024-08-04T20:46:45Z
dc.date.issued2019
dc.departmentİnönü Üniversitesien_US
dc.description.abstractBackground Cardiac resynchronization therapy (CRT) is recommended for patients with advanced chronic heart failure. Systolic aortic root motion (SARM) has been investigated in dilated cardiomyopathy patients and found that heart failure patients had reduced SARM. We aimed to investigate the relationship between SARM and response to CRT. Methods Fifty-six patients with advanced heart failure, wide QRS complex, and LVEF <= 35% were included. Transthoracic echocardiography was performed before, and repeated at 6 months in follow-up. Systolic aortic root motion was measured in each patient before the device implantation. Echocardiographic response to CRT was defined by a >= 15% reduction in left ventricular end-systolic volume at 6 months follow-up. Results Forty patients (71%) had CRT response after 6 months of follow-up. In multivariate analysis, significant associates of response to CRT was evaluated adjusting for functional capacity, etiology of cardiomyopathy, QRS duration, baseline left ventricular dimensions/volumes and SARM. SARM was the only predictor of response to CRT (OR 1.818, 95% CI, 1.101-3.003, P = .019). Conclusions SARM predicts non-response to CRT and may help in the selection of CRT candidates.en_US
dc.identifier.doi10.1111/pace.13792
dc.identifier.endpage1476en_US
dc.identifier.issn0147-8389
dc.identifier.issn1540-8159
dc.identifier.issue11en_US
dc.identifier.pmid31453634en_US
dc.identifier.scopus2-s2.0-85071750515en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage1471en_US
dc.identifier.urihttps://doi.org/10.1111/pace.13792
dc.identifier.urihttps://hdl.handle.net/11616/98941
dc.identifier.volume42en_US
dc.identifier.wosWOS:000493022400008en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherWileyen_US
dc.relation.ispartofPace-Pacing and Clinical Electrophysiologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectcardiac resynchronization therapyen_US
dc.subjectresponseen_US
dc.subjectsystolic aortic root motionen_US
dc.titleSystolic aortic root motion predicts response to cardiac resynchronization therapyen_US
dc.typeArticleen_US

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