Four-dimensional speckle tracking echocardiography and fragmented QRS in detection of early left ventricular systolic dysfunction in patients with subclinical hyperthyroidism

Basit Öğe Kaydı
dc.authoridkarasu, mehdi/0000-0003-1713-3451
dc.authoridKaraca, Yücel/0000-0002-5184-5308
dc.authorwosidkarasu, mehdi/ABK-4661-2022
dc.authorwosidKaraca, Yücel/AAA-4477-2022
dc.contributor.authorKaraca, Yucel
dc.contributor.authorKarasu, Mehdi
dc.contributor.authorTasolar, Hakan
dc.contributor.authorEvren, Bahri
dc.date.accessioned2024-08-04T20:53:36Z
dc.date.available2024-08-04T20:53:36Z
dc.date.issued2023
dc.departmentİnönü Üniversitesien_US
dc.description.abstractBackground: Thyroid disorders are associated with many cardiovascular risk factors. The importance of thyroid hormones in the pathophysiology of heart failure is underlined by the European guidelines of the European Society of Cardiology. However, the role of subclinical hyperthyroidism (SCH) in subclinical left ventricular (LV) systolic dysfunction is not entirely clear. Methods: This cross-sectional study included 56 SCH patients and 40 healthy volunteers. The 56 SCH group was divided into two subgroups depending on the presence of fragmented QRS (fQRS). In both groups, left ventricular global area strain (LV-GAS), global radial strain (GRS), global longitudinal strain (GLS), and global circumferential strain (GCS) were obtained with four-dimensional (4D) echocardiography. Results: GAS, GRS, GLS, and GCS values were significantly different in SCH patients and in healthy volunteers. GLS and GAS values were lower in the fQRS+ than in the fQRS- group (-17.06 +/- 1.00 vs. -19.08 +/- 1.71, p < .001, and -26.61 +/- 2.38 vs. -30.61 +/- 2.57, p < .001, respectively). ProBNP was positively correlated with LV-GLS (r = 0.278, p = .006) and LV-GAS (r = 0.357, p < .001). Multiple linear regression analysis showed that fQRS was an independent predictor of LV-GAS. Conclusions: 4D strain echocardiography may be helpful for the prediction of early cardiac dysfunction in patients with SCH. The presence of fQRS may be an indicator of subclinical LV dysfunction in SCH.en_US
dc.identifier.doi10.1002/jcu.23459
dc.identifier.endpage948en_US
dc.identifier.issn0091-2751
dc.identifier.issn1097-0096
dc.identifier.issue6en_US
dc.identifier.pmid37002782en_US
dc.identifier.scopus2-s2.0-85152058749en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage939en_US
dc.identifier.urihttps://doi.org/10.1002/jcu.23459
dc.identifier.urihttps://hdl.handle.net/11616/101281
dc.identifier.volume51en_US
dc.identifier.wosWOS:000962248500001en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherWileyen_US
dc.relation.ispartofJournal of Clinical Ultrasounden_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectfour-dimensional echocardiographyen_US
dc.subjectfragmented QRSen_US
dc.subjectsubclinical hyperthyroidismen_US
dc.titleFour-dimensional speckle tracking echocardiography and fragmented QRS in detection of early left ventricular systolic dysfunction in patients with subclinical hyperthyroidismen_US
dc.typeArticleen_US

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayın Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu