Evaluation of Salivary Glands by Ultrasonography and Inflammatory Markers in Children with Autoimmune Thyroiditis

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dc.authoridDemiröz Tasolar, Sevgi/0000-0002-9836-6814
dc.authoridSigirci, Ahmet/0000-0001-9221-0002;
dc.authorwosidDemiröz Tasolar, Sevgi/KTI-6349-2024
dc.authorwosidSigirci, Ahmet/ABG-7387-2020
dc.authorwosidÇiftci, Nurdan/GNM-8116-2022
dc.contributor.authorTasolar, Sevgi Demiroz
dc.contributor.authorSigirci, Ahmet
dc.contributor.authorCiftci, Nurdan
dc.contributor.authorCengiz, Aslinur
dc.contributor.authorDogan, Gulec Mert
dc.contributor.authorAkinci, Aysehan
dc.date.accessioned2024-08-04T20:11:44Z
dc.date.available2024-08-04T20:11:44Z
dc.date.issued2023
dc.departmentİnönü Üniversitesien_US
dc.description.abstractIntroduction: Although more common in adults, autoimmune thyroiditis (AT) is one of the most common thyroid diseases in children and adolescents. Salivary gland involvement has been described in many studies of patients with AT. Several inflammatory scores are used to assess the inflammatory status of patients with systemic autoimmune diseases. We aimed to sonographically evaluate the parotid and submandibular salivary glands with inflammatory parameters in patients with AT in our study. Methods: Our study population consisted of 37 consecutive pediatric AT patients and 29 healthy control subjects. Ultrasonographic and laboratory evaluations of the study population were performed. Jamovi and MedCalc software were used to analyze the data. Results: The volume of the thyroid gland in the patients was significantly higher than that in the control group (p=0.030), while there was no difference in the volume of the salivary glands. Multiple logistic regression analysis was planned to assess the predictability of salivary gland involvement in patients with the disease. Both systemic immune-inflammation index (SII) and pan-immune inflammation value (PIV) were found to be predictors of salivary gland involvement in AT patients. Conclusion: We found that both SII and PIV inflammatory markers are predictive of salivary gland parenchymal changes in patients with AT, and SII is likely to be more valuable than PIV at this time.en_US
dc.identifier.doi10.4274/imj.galenos.2023.31698
dc.identifier.endpage250en_US
dc.identifier.issn2619-9793
dc.identifier.issn2148-094X
dc.identifier.issue3en_US
dc.identifier.startpage246en_US
dc.identifier.trdizinid1243802en_US
dc.identifier.urihttps://doi.org/10.4274/imj.galenos.2023.31698
dc.identifier.urihttps://search.trdizin.gov.tr/yayin/detay/1243802
dc.identifier.urihttps://hdl.handle.net/11616/92961
dc.identifier.volume24en_US
dc.identifier.wosWOS:001063941300006en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakTR-Dizinen_US
dc.language.isoenen_US
dc.publisherGalenos Publ Houseen_US
dc.relation.ispartofIstanbul Medical Journalen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectAutoimmune thyroiditisen_US
dc.subjectglanden_US
dc.subjectparotiden_US
dc.subjectsubmandibularen_US
dc.subjectSIIen_US
dc.subjectPIVen_US
dc.titleEvaluation of Salivary Glands by Ultrasonography and Inflammatory Markers in Children with Autoimmune Thyroiditisen_US
dc.typeArticleen_US

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