Inspiratory capacity and forced expiratory volume in the first second in exacerbation of chronic obstructive pulmonary disease

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dc.authoridGunen, Hakan/0000-0001-6631-4457
dc.authorwosidGunen, Hakan/HKV-9202-2023
dc.contributor.authorYetkin, Ozkan
dc.contributor.authorGunen, Hakan
dc.date.accessioned2024-08-04T20:32:27Z
dc.date.available2024-08-04T20:32:27Z
dc.date.issued2008
dc.departmentİnönü Üniversitesien_US
dc.description.abstractObject. Periodic exacerbations of symptoms are the major cause of morbidity, mortality and health care costs in patients with chronic obstructive pulmonary disease (COPD). Dyspnea is the major factor affecting the comfort of patients in the exacerbation of COPI). In this study, we aimed to compare the value of forced expiratory volume in the first second (FEV1) and inspiratory capacity (IC) measured before and after treatment in exacerbations and in the improvement in clyspnea. Methods: Eighty-seven patients (male/female, 80/7; mean age, 63 +/- 7) with COPD exacerbation were included in this study. All subjects underwent spirometric tests on the first day and at the end of treatment. The subjects were asked to quantify the sensation of dyspnea that was described to them as a nonspecific discomfort associated with the act of breathing. The patients quantified dyspnea by pointing to a score on a large Borg scale from 0 to 10 arbitrary units. In the beginning and at the end of treatment, forced vital capacity (FVC), FEV1, forced expiratory flow rate between 25% and 75% of FVC (FEF25-75), peak expiratory flow rate (PEF), IC and Borg score (BS) values were compared. Results: After treatment of COPD exacerbations, FEV1, FEF25-75, PEF and IC significantly increased, and the BS significantly decreased compared to the initial values. The increase in IC was more significantly correlated with the improvement in BS compared with FEV1 Admission and discharge day BS was negatively correlated with FEV1, FEF25-75 and IC. Conclusion: We have shown a more dramatic improvement in IC compared with FEV, in patients treated as a result of acute exacerbation of COPD. These data suggest that IC may be more useful than FEV1 during acute exacerbation of COPD. Moreover, IC better reflects the severity of dyspnea. in these patients.en_US
dc.identifier.doi10.1111/j.1752-699X.2007.00040.x
dc.identifier.endpage40en_US
dc.identifier.issn1752-6981
dc.identifier.issn1752-699X
dc.identifier.issue1en_US
dc.identifier.pmid20298302en_US
dc.identifier.scopus2-s2.0-77954694893en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage36en_US
dc.identifier.urihttps://doi.org/10.1111/j.1752-699X.2007.00040.x
dc.identifier.urihttps://hdl.handle.net/11616/95085
dc.identifier.volume2en_US
dc.identifier.wosWOS:000257155800006en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherWileyen_US
dc.relation.ispartofClinical Respiratory Journalen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectacute exacerbationen_US
dc.subjectchronic obstructive pulmonary diseaseen_US
dc.subjectFEV1en_US
dc.subjectinspiratory capacityen_US
dc.titleInspiratory capacity and forced expiratory volume in the first second in exacerbation of chronic obstructive pulmonary diseaseen_US
dc.typeArticleen_US

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